This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-FLAG PTEN
catalog :
78777
citations: 6
Reference
Fernando S, Sellers J, Smith S, Bhogoju S, Junkins S, Welch M, et al. Metabolic Impact of MKP-2 Upregulation in Obesity Promotes Insulin Resistance and Fatty Liver Disease. Nutrients. 2022;14: pubmed publisher
Zhang K, Wang J, Wang J, Luh F, Liu X, Yang L, et al. LKB1 deficiency promotes proliferation and invasion of glioblastoma through activation of mTOR and focal adhesion kinase signaling pathways. Am J Cancer Res. 2019;9:1650-1663 pubmed
Katsuyama T, Li H, Comte D, Tsokos G, Moulton V. Splicing factor SRSF1 controls T cell hyperactivity and systemic autoimmunity. J Clin Invest. 2019;129:5411-5423 pubmed publisher
Melamed J, Morgan J, Ioele S, Gleghorn J, Sims Mourtada J, Day E. Investigating the role of Hedgehog/GLI1 signaling in glioblastoma cell response to temozolomide. Oncotarget. 2018;9:27000-27015 pubmed publisher
Yang L, Niu F, Yao H, Liao K, Chen X, Kook Y, et al. Exosomal miR-9 Released from HIV Tat Stimulated Astrocytes Mediates Microglial Migration. J Neuroimmune Pharmacol. 2018;13:330-344 pubmed publisher
Lee M, Jeong M, Lee H, Han H, Ko A, Hewitt S, et al. PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis. Nat Commun. 2015;6:7769 pubmed publisher
product information
Catalog Number :
78777
Product Name :
pcDNA3-FLAG PTEN
article :
doi10.1038/ncomms8769
id18477
pubmed_id26183061
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3-FLAG
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
To overexpress PTEN in Mammalian Cells
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3unknown
cloning_site_5unknown
promoterCMV
sequencing_primer_3BGHrev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliases10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, PTENbeta, TEP1
genePTEN
id5728
genbank_ids
mutation
namePTEN
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagFLAG
resistance markers :
2867
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA