This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Mouse Brie kinome pooled library, guides 1-4 in lentiGuide-Puro backbone
catalog :
75316
citations: 5
Reference
Pandey G, Landman N, Neikes H, Hulsman D, Lieftink C, Beijersbergen R, et al. Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma. Cell Rep Med. 2023;:100915 pubmed publisher
Lan B, Zeng S, Zhang S, Ren X, Xing Y, Kutschick I, et al. CRISPR-Cas9 Screen Identifies DYRK1A as a Target for Radiotherapy Sensitization in Pancreatic Cancer. Cancers (Basel). 2022;14: pubmed publisher
Piccioni F, Younger S, Root D. Pooled Lentiviral-Delivery Genetic Screens. Curr Protoc Mol Biol. 2018;121:32.1.1-32.1.21 pubmed publisher
Yau E, Rana T. Next-Generation Sequencing of Genome-Wide CRISPR Screens. Methods Mol Biol. 2018;1712:203-216 pubmed publisher
Doench J, Fusi N, Sullender M, Hegde M, Vaimberg E, Donovan K, et al. Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9. Nat Biotechnol. 2016;34:184-191 pubmed publisher
product information
Catalog Number :
75316
Product Name :
Mouse Brie kinome pooled library, guides 1-4 in lentiGuide-Puro backbone
article :
doi10.1038/nbt.3437
id16517
pubmed_id26780180
bacterial resistance :
Ampicillin
cloning :
backbonelentiGuide-Puro
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
growth strain :
Mouse sgRNA library in backbone lentiGuide-Puro targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls
origin :
37
pi :
alt_names
cloning
entrez_gene
genbank_ids
mutation
name2,852 unique sgRNAs targeting 713 mouse kinase genes along with 100 non-targeting controls
shRNA_sequence
size
species
tags
resistance markers :
2061
423
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA