This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-Flt3-Y591F/Y919F
catalog :
74497
citations: 1
Reference
Kazi J, Sun J, Phung B, Zadjali F, Flores Morales A, Ronnstrand L. Suppressor of cytokine signaling 6 (SOCS6) negatively regulates Flt3 signal transduction through direct binding to phosphorylated tyrosines 591 and 919 of Flt3. J Biol Chem. 2012;287:36509-17 pubmed publisher
product information
Catalog Number :
74497
Product Name :
pcDNA3-Flt3-Y591F/Y919F
article :
doi10.1074/jbc.M112.376111
id18058
pubmed_id22952242
bacterial resistance :
Ampicillin
cloning :
backbonepCDNA3
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 287, NO. 43, pp. 36509_36517, October 19, 2012
growth strain :
Overexpression of FLT3 Y591F/Y919F mutant in mammalian cells
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3unknown
cloning_site_5unknown
promoterCMV
sequencing_primer_3BGHrev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCD135, FLK-2, FLK2, STK1
geneFLT3
id2322
genbank_ids
mutationY591F/Y919F, T227M
nameFLT3
shRNA_sequence
size
species
9606
Homo sapiens
tags
resistance markers :
2779
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA