pLenti.CMV/TO_PRKAA1 | Addgene 74446 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pLenti.CMV/TO_PRKAA1

catalog :

74446

citations: 4

Reference
Pandit M, Kil Y, Ahn J, Pokhrel R, Gu Y, Mishra S, et al. Methionine consumption by cancer cells drives a progressive upregulation of PD-1 expression in CD4 T cells. Nat Commun. 2023;14:2593 pubmed publisher
van Vliet T, Varela Eirin M, Wang B, Borghesan M, Brandenburg S, Franzin R, et al. Physiological hypoxia restrains the senescence-associated secretory phenotype via AMPK-mediated mTOR suppression. Mol Cell. 2021;81:2041-2052.e6 pubmed publisher
Chen Q, Lei J, Bao J, Wang H, Hao W, Li L, et al. BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis. Adv Sci (Weinh). 2020;7:1903616 pubmed publisher
Toyama E, Herzig S, Courchet J, Lewis T, LosÃ³n O, Hellberg K, et al. Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress. Science. 2016;351:275-281 pubmed publisher

product information

Catalog Number :

74446

Product Name :

pLenti.CMV/TO_PRKAA1

article :

doi	10.1126/science.aab4138
id	18008
pubmed_id	26816379

bacterial resistance :

Ampicillin

cloning :

backbone

pLenti CMV/TO Puro empty (w175-1)

backbone_mutation

backbone_origin

Addgene plasmid 17482

backbone_size

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

Lentiviral

growth strain :

Lentiviral expression vector encoding untagged WT human AMPK alpha 1

origin :

pi :

alt_names

cloning

clone_method	Unknown
cloning_site_3
cloning_site_5
promoter	CMV
sequencing_primer_3	WPRE-R
sequencing_primer_5	CMV-F
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	AMPK, AMPK alpha 1, AMPKa1
gene	PRKAA1
id	5562

genbank_ids

mutation

name

AMPK alpha 1

shRNA_sequence

size

species

9606

Homo sapiens