This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCDNA3-STAT3-Y705F
catalog :
74434
citations: 4
Reference
Razidlo G, Burton K, McNiven M. Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42. J Biol Chem. 2018;293:11143-11153 pubmed publisher
Cheng X, Peuckert C, Wolfl S. Essential role of mitochondrial Stat3 in p38MAPK mediated apoptosis under oxidative stress. Sci Rep. 2017;7:15388 pubmed publisher
Yamamoto K, Shichiri H, Ishida T, Kaku K, Nishioka T, Kume M, et al. Effects of Ascorbyl-2-phosphate Magnesium on Human Keratinocyte Toxicity and Pathological Changes by Sorafenib. Biol Pharm Bull. 2017;40:1530-1536 pubmed publisher
Kim J, Yoon M, Chen J. Signal transducer and activator of transcription 3 (STAT3) mediates amino acid inhibition of insulin signaling through serine 727 phosphorylation. J Biol Chem. 2009;284:35425-32 pubmed publisher
product information
Catalog Number :
74434
Product Name :
pCDNA3-STAT3-Y705F
article :
doi10.1074/jbc.M109.051516
id16514
pubmed_id19875458
bacterial resistance :
Ampicillin
cloning :
backbonepCDNA3
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
E16K mutation originated in Plasmid #8706 but does not affect function. WT control for Plasmid 74434: pCDNA3-STAT3-Y705F is Plasmid 8706: Stat3 pcDNA3 from the Darnell lab.
growth strain :
Expression of STAT3-Y705F
origin :
37
pi :
alt_names
cloning
clone_methodUnknown
cloning_site_3
cloning_site_5
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
genbank_ids
NP_998824.1
mutationMutations E16K, Y705F
nameSignal Transducer And Activator Of Transcription 3 (Acute-Phase Response Factor)
shRNA_sequence
size
species
10090
Mus musculus
tags
locationC terminal on insert
tagFlag
resistance markers :
818
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA