This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCDNA3-HA-HA-humanCMYC
catalog :
74164
citations: 9
Reference
Sena L, Kumar R, Sanin D, Thompson E, Rosen D, Dalrymple S, et al. Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC. J Clin Invest. 2022;132: pubmed publisher
Nguyen T, Shang E, Shu C, Kim S, Mela A, Humala N, et al. Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma. Nat Commun. 2021;12:5203 pubmed publisher
Cho S, Lee G, Pickering B, Jang C, Park J, He L, et al. mTORC1 promotes cell growth via m6A-dependent mRNA degradation. Mol Cell. 2021;81:2064-2075.e8 pubmed publisher
Lee J, Wu Y, Harada B, Li Y, Zhao J, He C, et al. N6 -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness. EMBO J. 2021;40:e106276 pubmed publisher
Guo Y, Ye Q, Deng P, Cao Y, He D, Zhou Z, et al. Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression. Nat Commun. 2020;11:3243 pubmed publisher
Morel M, Shah K, Long W. The F-box protein FBXL16 up-regulates the stability of C-MYC oncoprotein by antagonizing the activity of the F-box protein FBW7. J Biol Chem. 2020;295:7970-7980 pubmed publisher
Weng H, Huang H, Wu H, Qin X, Zhao B, Dong L, et al. METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification. Cell Stem Cell. 2018;22:191-205.e9 pubmed publisher
Mukhopadhyay A, Hanold L, Thayele Purayil H, Gisemba S, Senadheera S, Aldrich J. Macrocyclic peptides decrease c-Myc protein levels and reduce prostate cancer cell growth. Cancer Biol Ther. 2017;18:571-583 pubmed publisher
Vo B, Wolf E, Kawauchi D, Gebhardt A, Rehg J, Finkelstein D, et al. The Interaction of Myc with Miz1 Defines Medulloblastoma Subgroup Identity. Cancer Cell. 2016;29:5-16 pubmed publisher
product information
Catalog Number :
74164
Product Name :
pCDNA3-HA-HA-humanCMYC
article :
doi10.1016/j.ccell.2015.12.003
id16558
pubmed_id26766587
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5440
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Mammalian expression of human cMyc
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3unknown
cloning_site_5unknown
promoterCMV
sequencing_primer_3BGHrev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMRTL, MYCC, bHLHe39, c-Myc
geneMYC
id4609
genbank_ids
P01106.1
mutation
namecMyc
shRNA_sequence
size1064
species
9606
Homo sapiens
tags
locationN terminal on insert
tag2x HA
resistance markers :
1113
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA