This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-Myc-AIM2
catalog :
73958
citations: 2
Reference
Yang Y, Zhang M, Jin C, Ding Y, Yang M, Wang R, et al. Absent in melanoma 2 suppresses epithelial-mesenchymal transition via Akt and inflammasome pathways in human colorectal cancer cells. J Cell Biochem. 2019;: pubmed publisher
Khare S, Ratsimandresy R, de Almeida L, Cuda C, Rellick S, Misharin A, et al. The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses. Nat Immunol. 2014;15:343-53 pubmed publisher
product information
Catalog Number :
73958
Product Name :
pcDNA3-Myc-AIM2
article :
doi10.1038/ni.2829
id17875
pubmed_id24531343
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutationA c-myc tag and a modified MCS were inserted as indicated in the attached plasmid map.
backbone_origin
backbone_size5459
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Express c-Myc-tagged human AIM2 in mammalian cells
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3Xho1
cloning_site_5BamH1
promoterCMV iE
sequencing_primer_3SP6 promoter (ATTTAGGTGACACTATAG)
sequencing_primer_5T7 promoter (TAATACGACTCACTATAGGG)
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesPYHIN4
geneAIM2
id9447
genbank_ids
NM_004833.1
mutation
nameabsent in melanoma 2 (AIM2)
shRNA_sequence
size1050
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagc-myc
resistance markers :
2763
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA