This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Progerin-S22D-CS-pLPC
catalog :
73810
citations: 1
Reference
Moiseeva O, Lopes Paciencia S, Huot G, Lessard F, Ferbeyre G. Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase. Aging (Albany NY). 2016;8:366-81 pubmed
product information
Catalog Number :
73810
Product Name :
Progerin-S22D-CS-pLPC
article :
doi10.18632/aging.100903
id28192038
pubmed_id26922519
bacterial resistance :
Ampicillin
cloning :
backbonepLPC
backbone_mutation
backbone_origin
backbone_size5493
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth strain :
Progerin mutant where Serine 22 is mutated to aspartic acid and where there is a substitution of cysteine in CaaX-motif by a serine
origin :
37
pi :
alt_names
cloning
clone_methodUnknown
cloning_site_3
cloning_site_5
promoterCMV
sequencing_primer_3acctgtaggtttggcaag
sequencing_primer_5taggcgtgtacggtggga
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, MADA, PRO1
geneLMNA
id4000
genbank_ids
mutationProgerin with substitution of cysteine in CaaX-motif by serine (C to S) and S22D mutation
nameProgerin
shRNA_sequence
size1845
species
9606
Homo sapiens
tags
resistance markers :
1991
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA