This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCDNA3-HA-Akt1
catalog :
73408
citations: 14
Reference
Wu X, Zhang Z, Wong J, Rivera Soto R, White M, Rai A, et al. Kaposi's sarcoma-associated herpesvirus viral protein kinase augments cell survival. Cell Death Dis. 2023;14:688 pubmed publisher
Bonavita R, Scerra G, Di Martino R, Nuzzo S, Polishchuk E, Di Gennaro M, et al. The HSPB1-p62/SQSTM1 functional complex regulates the unconventional secretion and transcellular spreading of the HD-associated mutant huntingtin protein. Hum Mol Genet. 2023;32:2269-2291 pubmed publisher
Li M, Gao F, Li X, Gan Y, Han S, Yu X, et al. Stabilization of MCL-1 by E3 ligase TRAF4 confers radioresistance. Cell Death Dis. 2022;13:1053 pubmed publisher
Chen M, Choi S, Wen T, Chen C, Thapa N, Lee J, et al. A p53-phosphoinositide signalosome regulates nuclear AKT activation. Nat Cell Biol. 2022;24:1099-1113 pubmed publisher
Cha Y, Kim T, Jeon J, Jang Y, Kim P, Lopes C, et al. SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes. Cell Rep. 2021;37:110155 pubmed publisher
Ocklenburg T, Neumann F, Wolf A, Vogel J, Göpelt K, Baumann M, et al. In oxygen-deprived tumor cells ERp57 provides radioprotection and ensures proliferation via c-Myc, PLK1 and the AKT pathway. Sci Rep. 2021;11:7199 pubmed publisher
Li T, Wang X, Ju E, da Silva S, Chen L, Zhang X, et al. RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation. Nat Commun. 2021;12:1055 pubmed publisher
Zhao J, Zhu L, Wijesekera N, Jones C. Specific Akt Family Members Impair Stress-Mediated Transactivation of Viral Promoters and Enhance Neuronal Differentiation: Important Functions for Maintaining Latency. J Virol. 2020;94: pubmed publisher
Yu X, Li W, Liu H, Deng Q, Wang X, Hu H, et al. Ubiquitination of the DNA-damage checkpoint kinase CHK1 by TRAF4 is required for CHK1 activation. J Hematol Oncol. 2020;13:40 pubmed publisher
Butt E, Stempfle K, Lister L, Wolf F, Kraft M, Herrmann A, et al. Phosphorylation-Dependent Differences in CXCR4-LASP1-AKT1 Interaction between Breast Cancer and Chronic Myeloid Leukemia. Cells. 2020;9: pubmed publisher
Peng T, Qiao M, Liu H, Teotia S, Zhang Z, Zhao Y, et al. A Resource for Inactivation of MicroRNAs Using Short Tandem Target Mimic Technology in Model and Crop Plants. Mol Plant. 2018;11:1400-1417 pubmed publisher
Workman A, Zhu L, Keel B, Smith T, Jones C. The Wnt Signaling Pathway Is Differentially Expressed during the Bovine Herpesvirus 1 Latency-Reactivation Cycle: Evidence That Two Protein Kinases Associated with Neuronal Survival, Akt3 and BMPR2, Are Expressed at Higher Levels during Latency. J Virol. 2018;92: pubmed publisher
Wang J, Ye Q, Cao Y, Guo Y, Huang X, Mi W, et al. Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1. Nat Commun. 2017;8:2207 pubmed publisher
Zeng M, van der Donk W, Chen J. Lanthionine synthetase C-like protein 2 (LanCL2) is a novel regulator of Akt. Mol Biol Cell. 2014;25:3954-61 pubmed publisher
product information
Catalog Number :
73408
Product Name :
pCDNA3-HA-Akt1
article :
doi10.1091/mbc.E14-01-0004
id14043
pubmed_id25273559
bacterial resistance :
Ampicillin
cloning :
backbonepCDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expresses human AKT1 with a N-terminus HA tag
origin :
37
pi :
alt_names
cloning
clone_methodUnknown
cloning_site_3
cloning_site_5
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAKT, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
geneAKT1
id207
genbank_ids
mutation
nameAKT1
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on insert
tagHA tag
resistance markers :
818
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA