pCDNA3-STAT3-S727D | Addgene 73364 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pCDNA3-STAT3-S727D

catalog :

73364

citations: 4

Reference
Zukowski E, Sannella M, Rockhold J, Kalantar G, Yu J, SantaCruz Calvo S, et al. STAT3 modulates CD4+ T mitochondrial dynamics and function in aging. Aging Cell. 2023;22:e13996 pubmed publisher
De Virgiliis F, Hutson T, Palmisano I, Amachree S, Miao J, Zhou L, et al. Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling. Nat Commun. 2020;11:6425 pubmed publisher
Cheng X, Peuckert C, Wolfl S. Essential role of mitochondrial Stat3 in p38MAPK mediated apoptosis under oxidative stress. Sci Rep. 2017;7:15388 pubmed publisher
Kim J, Yoon M, Chen J. Signal transducer and activator of transcription 3 (STAT3) mediates amino acid inhibition of insulin signaling through serine 727 phosphorylation. J Biol Chem. 2009;284:35425-32 pubmed publisher

product information

Catalog Number :

73364

Product Name :

pCDNA3-STAT3-S727D

article :

doi	10.1074/jbc.M109.051516
id	16514
pubmed_id	19875458

bacterial resistance :

Ampicillin

cloning :

backbone

pCDNA3

backbone_mutation

backbone_origin

backbone_size

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

growth notes :

E16K mutation originated in Plasmid #8706 but does not affect function. WT control for Plasmid 73364: pCDNA3-STAT3-S727D is Plasmid 8706: Stat3 pcDNA3 from the Darnell lab.

growth strain :

Expression of STAT3-S727D

origin :

pi :

alt_names

cloning

clone_method	Unknown
cloning_site_3
cloning_site_5
promoter	CMV
sequencing_primer_3	BGH-rev
sequencing_primer_5	CMV-F
site_3_destroyed
site_5_destroyed

entrez_gene

genbank_ids

NP_998824.1

mutation

E16K S727D

name

Signal Transducer And Activator Of Transcription 3 (Acute-Phase Response Factor)

shRNA_sequence

size

species

10090

Mus musculus