This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLEGFP-WT-STAT3
catalog :
71450
citations: 11
Reference
Wan Z, Li X, Luo X, Wang B, Zhou X, Chen A. The miR-590-3p/CFHR3/STAT3 signaling pathway promotes cell proliferation and metastasis in hepatocellular carcinoma. Aging (Albany NY). 2022;14:5783-5799 pubmed publisher
LI Y, Fahrmann J, Aftabizadeh M, Zhao Q, Tripathi S, Zhang C, et al. Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids. Cell Rep. 2022;39:110870 pubmed publisher
Wang L, Astone M, Alam S, Zhu Z, Pei W, Frank D, et al. Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability. Dis Model Mech. 2021;14: pubmed publisher
Chen W, Patel D, Jia Y, Yu Z, Liu X, Shi H, et al. MARCH8 Suppresses Tumor Metastasis and Mediates Degradation of STAT3 and CD44 in Breast Cancer Cells. Cancers (Basel). 2021;13: pubmed publisher
De Virgiliis F, Hutson T, Palmisano I, Amachree S, Miao J, Zhou L, et al. Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling. Nat Commun. 2020;11:6425 pubmed publisher
Hou J, Zhao R, Xia W, Chang C, You Y, Hsu J, et al. PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis. Nat Cell Biol. 2020;22:1264-1275 pubmed publisher
He H, Zhuo R, Dai J, Wang X, Huang X, Wang H, et al. Chelerythrine induces apoptosis via ROS-mediated endoplasmic reticulum stress and STAT3 pathways in human renal cell carcinoma. J Cell Mol Med. 2020;24:50-60 pubmed publisher
Sang Y, Li Y, Zhang Y, Alvarez A, Yu B, Zhang W, et al. CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity. Nat Commun. 2019;10:4013 pubmed publisher
Sang Y, Li Y, Song L, Alvarez A, Zhang W, Lv D, et al. TRIM59 Promotes Gliomagenesis by Inhibiting TC45 Dephosphorylation of STAT3. Cancer Res. 2018;78:1792-1804 pubmed publisher
Lv D, Li Y, Zhang W, Alvarez A, Song L, Tang J, et al. TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma. Nat Commun. 2017;8:1454 pubmed publisher
Dasgupta M, Unal H, Willard B, Yang J, Karnik S, Stark G. Critical role for lysine 685 in gene expression mediated by transcription factor unphosphorylated STAT3. J Biol Chem. 2014;289:30763-71 pubmed publisher
product information
Catalog Number :
71450
Product Name :
pLEGFP-WT-STAT3
article :
doi10.1074/jbc.M114.603894
id16109
pubmed_id25217633
bacterial resistance :
Ampicillin
cloning :
backbonepLEGFP-N1-neo
backbone_mutation
backbone_originClontech
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Retroviral
growth strain :
Retroviral expression of WT-STAT3. Please note that this plasmid contains WT-STAT3 tagged with FLAG, not GFP.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3unknown
cloning_site_5HindIII
promoterCMV
sequencing_primer_3EGFP-N
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesADMIO, ADMIO1, APRF, HIES
geneSTAT3
id6774
genbank_ids
mutation
nameSTAT3
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagFLAG
resistance markers :
2634
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA