This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLEGFP-K49R-STAT3
catalog :
71447
citations: 2
Reference
Muller A, Dickmanns A, Resch C, Schakel K, Hailfinger S, Dobbelstein M, et al. The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. J Clin Invest. 2020;: pubmed publisher
Dasgupta M, Dermawan J, Willard B, Stark G. STAT3-driven transcription depends upon the dimethylation of K49 by EZH2. Proc Natl Acad Sci U S A. 2015;112:3985-90 pubmed publisher
product information
Catalog Number :
71447
Product Name :
pLEGFP-K49R-STAT3
article :
doi10.1073/pnas.1503152112
id16010
pubmed_id25767098
bacterial resistance :
Ampicillin
cloning :
backbonepLEGFP-N1-neo
backbone_mutation
backbone_originClontech
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Retroviral
growth strain :
Retroviral expression of K49R-STAT3. Please note that this plasmid contains K49R-STAT3 tagged with FLAG, not GFP.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3unknown
cloning_site_5HindIII
promoterCMV
sequencing_primer_3EGFP-N
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesADMIO, ADMIO1, APRF, HIES
geneSTAT3
id6774
genbank_ids
mutationK49R
nameSTAT3
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagFLAG
resistance markers :
2634
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA