This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
R777-E061 Hs.ERBB2
catalog :
70345
citations: 1
Reference
Ho C, Tüns A, Schildhaus H, Wiesweg M, Grüner B, Hegedus B, et al. HER2 mediates clinical resistance to the KRASG12C inhibitor sotorasib, which is overcome by co-targeting SHP2. Eur J Cancer. 2021;159:16-23 pubmed publisher
product information
Catalog Number :
70345
Product Name :
R777-E061 Hs.ERBB2
article :
doi
id15959
pubmed_id
bacterial resistance :
Spectinomycin
cloning :
backbonepDonor-255
backbone_mutation
backbone_origin
backbone_size2693
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Other
Gateway Entry Clone
growth strain :
Gateway ORF clone of human ERBB2 [NM_004448.3] with stop codon (for native or N-terminal fusions)
origin :
37
pi :
alt_names
NM_004448.3
cloning
clone_methodGateway Cloning
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3attLR 23-mer (5'-TAACATCAGAGATTTTGAGACAC)
sequencing_primer_5M13F 23-mer (5'-CCCAGTCACGACGTTGTAAAACG)
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2)
geneERBB2
id2064
genbank_ids
mutation
nameERBB2
shRNA_sequence
size3768
species
9606
Homo sapiens
tags
resistance markers :
139
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA