This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pEGFP-n1-AICD
catalog :
69925
citations: 3
Reference
Iannuzzi F, Sirabella R, Canu N, Maier T, Annunziato L, Matrone C. Fyn Tyrosine Kinase Elicits Amyloid Precursor Protein Tyr682 Phosphorylation in Neurons from Alzheimer's Disease Patients. Cells. 2020;9: pubmed publisher
Law B, Guest A, Pullen M, Perkinton M, Williams R. Increased Foxo3a Nuclear Translocation and Activity is an Early Neuronal Response to βγ-Secretase-Mediated Processing of the Amyloid-β Protein Precursor: Utility of an AβPP-GAL4 Reporter Assay. J Alzheimers Dis. 2018;61:673-688 pubmed publisher
Currinn H, Guscott B, Balklava Z, Rothnie A, Wassmer T. APP controls the formation of PI(3,5)P(2) vesicles through its binding of the PIKfyve complex. Cell Mol Life Sci. 2016;73:393-408 pubmed publisher
product information
Catalog Number :
69925
Product Name :
pEGFP-n1-AICD
article :
doi10.1007/s00018-015-1993-0
id15825
pubmed_id26216398
bacterial resistance :
Kanamycin
cloning :
backbonepEGFP-N1
backbone_mutation
backbone_originClontech
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
mammalian expression of human AICD fused to EGFP
origin :
37
pi :
alt_names
APP intracellular domain
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5NheI
promoterCMV
sequencing_primer_3EGFP-N
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, alpha-sAPP, preA4
geneAPP
id351
genbank_ids
mutation47 aa long
nameAICD
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagEGFP
resistance markers :
2573
2572
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA