This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pEGFP-n1-APP
catalog :
69924
citations: 9
Reference
Yang S, Niou Z, Enriquez A, LaMar J, Huang J, Ling K, et al. NMNAT2 supports vesicular glycolysis via NAD homeostasis to fuel fast axonal transport. Res Sq. 2023;: pubmed publisher
Raj N, Greune L, Kahms M, Mildner K, Franzkoch R, Psathaki O, et al. Early Endosomes Act as Local Exocytosis Hubs to Repair Endothelial Membrane Damage. Adv Sci (Weinh). 2023;10:e2300244 pubmed publisher
Li Y, Geng J, Rimal S, Wang H, Liu X, Lu B, et al. The mTORC2/AKT/VCP axis is associated with quality control of the stalled translation of poly(GR) dipeptide repeats in C9-ALS/FTD. J Biol Chem. 2023;299:102995 pubmed publisher
Conze C, Rierola M, Trushina N, Peters M, Janning D, Holzer M, et al. Caspase-cleaved tau is senescence-associated and induces a toxic gain of function by putting a brake on axonal transport. Mol Psychiatry. 2022;27:3010-3023 pubmed publisher
Reveglia P, Nasso R, Angiolillo A, Lecce L, Paolillo C, De Tullio S, et al. Tandem Mass Spectrometry as Strategy for the Selective Identification and Quantification of the Amyloid Precursor Protein Tyr682 Residue Phosphorylation Status in Human Blood Mononuclear Cells. Biomolecules. 2021;11: pubmed publisher
Naughton S, Beck W, Wei Z, Wu G, Baas P, Terry A. The Carbamate, Physostigmine does not Impair Axonal Transport in Rat Cortical Neurons. Neurosci Insights. 2021;16:26331055211020289 pubmed publisher
Iannuzzi F, Sirabella R, Canu N, Maier T, Annunziato L, Matrone C. Fyn Tyrosine Kinase Elicits Amyloid Precursor Protein Tyr682 Phosphorylation in Neurons from Alzheimer's Disease Patients. Cells. 2020;9: pubmed publisher
Wu X, Chen S, Lu C. Amyloid precursor protein promotes the migration and invasion of breast cancer cells by regulating the MAPK signaling pathway. Int J Mol Med. 2019;: pubmed publisher
Currinn H, Guscott B, Balklava Z, Rothnie A, Wassmer T. APP controls the formation of PI(3,5)P(2) vesicles through its binding of the PIKfyve complex. Cell Mol Life Sci. 2016;73:393-408 pubmed publisher
product information
Catalog Number :
69924
Product Name :
pEGFP-n1-APP
article :
doi10.1007/s00018-015-1993-0
id15825
pubmed_id26216398
bacterial resistance :
Kanamycin
cloning :
backbonepEGFP-N1
backbone_mutation
backbone_originClontech
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
mammalian expression of human APP fused to EGFP
origin :
37
pi :
alt_names
APP695
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5NheI
promoterCMV
sequencing_primer_3EGFP-N
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, alpha-sAPP, preA4
geneAPP
id351
genbank_ids
mutation
nameAPP
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagEGFP
resistance markers :
2573
2572
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA