This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
plenti-CAG-IKZF1-V1-Q146H-FLAG-IRES-GFP
catalog :
69048
citations: 2
Reference
Aubrey B, Cutler J, Bourgeois W, Donovan K, Gu S, Hatton C, et al. IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia. Nat Cancer. 2022;3:595-613 pubmed publisher
Lu G, Middleton R, Sun H, Naniong M, Ott C, Mitsiades C, et al. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. Science. 2014;343:305-9 pubmed publisher
product information
Catalog Number :
69048
Product Name :
plenti-CAG-IKZF1-V1-Q146H-FLAG-IRES-GFP
article :
doi10.1126/science.1244917
id8472
pubmed_id24292623
bacterial resistance :
Kanamycin
cloning :
backboneplenti-CAG -IRES-GFP
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
growth strain :
lentiviral expression of IKZF1 variant 1 with Q146H mutation and FLAG tag
origin :
30
pi :
alt_names
IKAROS family zinc finger 1
cloning
clone_methodGateway Cloning
cloning_site_3
cloning_site_5
promoterCAG
sequencing_primer_3pCDH-rev
sequencing_primer_5pCAG-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCVID13, Hs.54452, IK1, IKAROS, LYF1, LyF-1, PPP1R92, PRO0758, ZNFN1A1
geneIKZF1
id10320
genbank_ids
mutationsplice variant 1, Q146H
nameIKZF1
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on insert
tagFLAG
locationC terminal on backbone
tagIRES-GFP
resistance markers :
238
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA