pQ398X-EGFP | Addgene 68849 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pQ398X-EGFP

catalog :

68849

citations: 2

Reference
Moore A, Holzbaur E. Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy. Proc Natl Acad Sci U S A. 2016;113:E3349-58 pubmed publisher
Turturro S, Shen X, Shyam R, YUE B, Ying H. Effects of mutations and deletions in the human optineurin gene. Springerplus. 2014;3:99 pubmed publisher

product information

Catalog Number :

68849

Product Name :

pQ398X-EGFP

article :

doi	845 [pii]
id	15593
pubmed_id	24683533

bacterial resistance :

Kanamycin

cloning :

backbone

pEGFP-C1

backbone_mutation

backbone_origin

Clontech

backbone_size

4733

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

growth notes :

Wild type construct is pOPTN-EGFP (Plasmid #27052)

growth strain :

mutated OPTN was inserted into pEGFP-N1 backbone

origin :

pi :

alt_names

OPTN

cloning

clone_method	Restriction Enzyme
cloning_site_3	BamHI
cloning_site_5	EcoRI
promoter	CMV
sequencing_primer_3	EGFP-N
sequencing_primer_5	CMV-F
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	ALS12, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP
gene	OPTN
id	10133

genbank_ids

mutation

Q398X, results in truncation of the protein into a 1-398 fragment

name

optineurin

shRNA_sequence

size

species

9606

Homo sapiens