This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCW57.1-FOXM1b
catalog :
68811
citations: 6
Reference
Hirschler Laszkiewicz I, Festa F, Huang S, Moldovan G, Nicolae C, Dhoonmoon A, et al. The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1. Sci Rep. 2022;12:6311 pubmed publisher
Chen H, Yu Y, Yang M, Huang H, Ma S, Hu J, et al. YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner. Cell Biosci. 2022;12:19 pubmed publisher
Haque M, Li J, Huang Y, Almowaled M, Barger C, Karpf A, et al. NPM-ALK Is a Key Regulator of the Oncoprotein FOXM1 in ALK-Positive Anaplastic Large Cell Lymphoma. Cancers (Basel). 2019;11: pubmed publisher
Song S, Zhang R, Cao W, Fang G, Yu Y, Wan Y, et al. Foxm1 is a critical driver of TGF-β-induced EndMT in endothelial cells through Smad2/3 and binds to the Snail promoter. J Cell Physiol. 2019;234:9052-9064 pubmed publisher
Wang K, Zhu X, Yao Y, Yang M, Zhou F, Zhu L. Corosolic acid induces cell cycle arrest and cell apoptosis in human retinoblastoma Y-79 cells via disruption of MELK-FoxM1 signaling. Oncol Rep. 2018;39:2777-2786 pubmed publisher
Barger C, Zhang W, Hillman J, Stablewski A, Higgins M, Vanderhyden B, et al. Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression. Oncotarget. 2015;6:27613-27 pubmed publisher
product information
Catalog Number :
68811
Product Name :
pCW57.1-FOXM1b
article :
doi4546 [pii]
id15575
pubmed_id26243836
bacterial resistance :
Ampicillin
cloning :
backbonepCW57.1
backbone_mutation
backbone_originBroad Insitute
backbone_size7667
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
Other
Doxycycline inducible
growth notes :
Note: The plasmid is derived from a FOXM1b cDNA clone from Origene which contains a SNP which causes a serine to proline amino acid residue substitution. This residue change is a natural variant and does not affect plasmid function.
growth strain :
Doxycycline inducible lentiviral vector for FOXM1b expression in mammalian cells
origin :
37
pi :
alt_names
Forkhead Box M1b
FOXM1
Forkhead Box M1
cloning
clone_methodGateway Cloning
cloning_site_3
cloning_site_5
promoterTRE promoter, Tet ON
sequencing_primer_3O.PGK1b-R (5'-GAACGGACGTGAAGAATGTG-3')
sequencing_primer_5LNCX (5'-AGCTCGTTTAGTGAACCGTCAGATC-3')
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesFKHL16, FOXM1A, FOXM1B, FOXM1C, HFH-11, HFH11, HNF-3, INS-1, MPHOSPH2, MPP-2, MPP2, PIG29, TRIDENT
geneFOXM1
id2305
genbank_ids
NM_202003.2
mutation
nameFOXM1b
shRNA_sequence
size2407
species
9606
Homo sapiens
tags
locationN terminal on insert
tagHA
plasmid copy :
The human FOXM1b open reading frame was subcloned from Origene FOXM1b cDNA construct (Cat SC128214 ) into Origene (Cat PS100013) pCMV6-AN-HA then finally subcloned into pCW57.1.
resistance markers :
2517
tags :
Unknown
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA