This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
4XCLEAR-luciferase reporter
catalog :
66800
citations: 7
Reference
Tejwani L, Jung Y, Kokubu H, Sowmithra S, Ni L, Lee C, et al. Reduction of Nemo-like kinase increases lysosome biogenesis and ameliorates TDP-43-related neurodegeneration. J Clin Invest. 2023;: pubmed publisher
Yang J, Xu H, Zhang C, Yang X, Cai W, Chen X. A prion-like domain of TFEB mediates the co-aggregation of TFEB and mHTT. Autophagy. 2022;:1-7 pubmed publisher
El Houjeiri L, Biondini M, Paquette M, Kuasne H, Pacis A, Park M, et al. Folliculin impairs breast tumor growth by repressing TFE3-dependent induction of the Warburg effect and angiogenesis. J Clin Invest. 2021;131: pubmed publisher
Paquette M, El Houjeiri L, C Zirden L, Puustinen P, Blanchette P, Jeong H, et al. AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE3. Autophagy. 2021;:1-19 pubmed publisher
Mohamud Y, Tang H, Xue Y, Liu H, Ng C, Bahreyni A, et al. Coxsackievirus B3 targets TFEB to disrupt lysosomal function. Autophagy. 2021;:1-15 pubmed publisher
Binder J, Chander P, Deretic V, Weick J, Bhaskar K. Optical induction of autophagy via Transcription factor EB (TFEB) reduces pathological tau in neurons. PLoS ONE. 2020;15:e0230026 pubmed publisher
Cortes C, Miranda H, Frankowski H, Batlevi Y, Young J, Le A, et al. Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA. Nat Neurosci. 2014;17:1180-9 pubmed publisher
product information
Catalog Number :
66800
Product Name :
4XCLEAR-luciferase reporter
article :
doi10.1038/nn.3787
id14418
pubmed_id25108912
bacterial resistance :
Ampicillin
cloning :
backbonepGL3
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Luciferase
growth strain :
Reporter for activity of the CLEAR network
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3Unknown
cloning_site_5Unknown
promoterFour CLEAR elements (GTCACGTGAC) in tandem derived from LAMP-1 promoter + HTK
sequencing_primer_3
sequencing_primer_5-
site_3_destroyed
site_5_destroyed
entrez_gene
genbank_ids
mutation
name4XCLEAR
shRNA_sequence
size
species
10090
Mus musculus
tags
resistance markers :
2415
tags :
Low Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA