This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pBGSA FPR1 N297A
catalog :
66723
citations: 1
Reference
Gripentrog J, Miettinen H. Formyl peptide receptor-mediated ERK1/2 activation occurs through G(i) and is not dependent on beta-arrestin1/2. Cell Signal. 2008;20:424-31 pubmed
product information
Catalog Number :
66723
Product Name :
pBGSA FPR1 N297A
article :
doi10.1016/j.cellsig.2007.11.002
id10431
pubmed_id18060741
bacterial resistance :
Ampicillin
cloning :
backbonepBSSK+
backbone_mutationExtensively modified
backbone_originStratagene
backbone_size7200
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
This mutant is defective in phosphorylation and beta-arrestin binding which leads to a defect in desensitization. Also associated with PMID: 11085933.
growth strain :
Constitutive expression of FPR1 N297A in mammalian cells.
origin :
37
pi :
alt_names
FMLP-R26
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoterSR-alpha
sequencing_primer_35'-TCTAGAACTAGTGGATCC-3'
sequencing_primer_55'-CTTCTAGGCCTGTACGG-3'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesFMLP, FPR
geneFPR1
id2357
genbank_ids
M60627
mutationN297A
nameFPR1 (haplotype 3)
shRNA_sequence
size1320
species
9606
Homo sapiens
tags
resistance markers :
2234
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA