This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pIRESpuro2 AXL
catalog :
65627
citations: 4
Reference
Das I, Gad H, Bräutigam L, Pudelko L, Tuominen R, Höiom V, et al. AXL and CAV-1 play a role for MTH1 inhibitor TH1579 sensitivity in cutaneous malignant melanoma. Cell Death Differ. 2020;27:2081-2098 pubmed publisher
Spencer J, Lahon A, Tran L, Arya R, Kneubehl A, Vogt M, et al. Replication of Zika Virus in Human Prostate Cells: A Potential Source of Sexually Transmitted Virus. J Infect Dis. 2018;217:538-547 pubmed publisher
Antony J, Tan T, Kelly Z, Low J, Choolani M, Recchi C, et al. The GAS6-AXL signaling network is a mesenchymal (Mes) molecular subtype-specific therapeutic target for ovarian cancer. Sci Signal. 2016;9:ra97 pubmed
Meyer A, Zweemer A, Lauffenburger D. The AXL Receptor is a Sensor of Ligand Spatial Heterogeneity. Cell Syst. 2015;1:25-36 pubmed
product information
Catalog Number :
65627
Product Name :
pIRESpuro2 AXL
article :
doi10.1016/j.cels.2015.06.002
id15924
pubmed_id26236777
bacterial resistance :
Ampicillin
cloning :
backbonepIRESpuro2
backbone_mutation
backbone_originCloneTech
backbone_size5000
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expresses AXL on cistronic transcript with puro resistance in mammalian cells
origin :
37
pi :
alt_names
AXL
UFO
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5NheI
promoterCMV
sequencing_primer_3
sequencing_primer_5CGCAAATGGGCGGTAGGCGTG
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesARK, AXL3, JTK11, Tyro7, UFO
geneAXL
id558
genbank_ids
NM_001699.5
mutationSpurious PDPRPHR on C terminus
nameTyrosine-protein kinase receptor UFO
shRNA_sequence
size2838
species
9606
Homo sapiens
tags
resistance markers :
2372
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA