This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
IRES-GFP-AXL-KD
catalog :
65498
citations: 3
Reference
Ye G, Huang M, Li Y, Ouyang J, Chen M, Wen Q, et al. The FAP α -activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway. Acta Pharm Sin B. 2022;12:1288-1304 pubmed publisher
Antony J, Tan T, Kelly Z, Low J, Choolani M, Recchi C, et al. The GAS6-AXL signaling network is a mesenchymal (Mes) molecular subtype-specific therapeutic target for ovarian cancer. Sci Signal. 2016;9:ra97 pubmed
Meyer A, Zweemer A, Lauffenburger D. The AXL Receptor is a Sensor of Ligand Spatial Heterogeneity. Cell Syst. 2015;1:25-36 pubmed
product information
Catalog Number :
65498
Product Name :
IRES-GFP-AXL-KD
article :
doi10.1016/j.cels.2015.06.002
id15924
pubmed_id26236777
bacterial resistance :
Kanamycin
cloning :
backbonepIRES2-EGFP
backbone_mutation
backbone_originClonetech
backbone_size5300
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expresses kinase dead AXL in mammalian cells with cistronic EGFP
origin :
37
pi :
alt_names
AXL
UFO
AXL oncogene
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5NheI
promoterCMV
sequencing_primer_3CTGGTCGAGCTGGACGGCGACG
sequencing_primer_5CGCAAATGGGCGGTAGGCGTG
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesARK, AXL3, JTK11, Tyro7, UFO
geneAXL
id558
genbank_ids
AAH32229.1
mutationK567R
nameTyrosine-protein kinase receptor UFO
shRNA_sequence
size2682
species
9606
Homo sapiens
tags
locationC terminal on insert
tagFLAG
resistance markers :
2372
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA