This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLPCX mito Grx1-roGFP2
catalog :
64977
citations: 12
Reference
Kidwell C, Casalini J, Pradeep S, Scherer S, Greiner D, Bayık D, et al. Transferred mitochondria accumulate reactive oxygen species, promoting proliferation. elife. 2023;12: pubmed publisher
Zulkifli M, Spelbring A, Zhang Y, Soma S, Chen S, Li L, et al. FDX1-dependent and independent mechanisms of elesclomol-mediated intracellular copper delivery. Proc Natl Acad Sci U S A. 2023;120:e2216722120 pubmed publisher
Hatori Y, Kanda Y, Nonaka S, Nakanishi H, Kitazawa T. ATP13A2 modifies mitochondrial localization of overexpressed TOM20 to autolysosomal pathway. PLoS ONE. 2022;17:e0276823 pubmed publisher
Zhang Y, Wen M, Qin G, Cai C, Chen T. Subcellular redox responses reveal different Cu-dependent antioxidant defenses between mitochondria and cytosol. Metallomics. 2022;14: pubmed publisher
Umansky C, Morellato A, Rieckher M, Scheidegger M, Martinefski M, Fernández G, et al. Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity. Nat Commun. 2022;13:745 pubmed publisher
Fernández Puente E, Palomero J. Genetically Encoded Biosensors to Monitor Intracellular Reactive Oxygen and Nitrogen Species and Glutathione Redox Potential in Skeletal Muscle Cells. Int J Mol Sci. 2021;22: pubmed publisher
Demmings M, Tennyson E, Petroff G, Tarnowski Garner H, Cregan S. Activating transcription factor-4 promotes neuronal death induced by Parkinson's disease neurotoxins and α-synuclein aggregates. Cell Death Differ. 2020;: pubmed publisher
Antonucci S, Di Sante M, Tonolo F, Pontarollo L, Scalcon V, Alánová P, et al. The Determining Role of Mitochondrial Reactive Oxygen Species Generation and Monoamine Oxidase Activity in Doxorubicin-Induced Cardiotoxicity. Antioxid Redox Signal. 2020;: pubmed publisher
Luciani A, Schumann A, Berquez M, Chen Z, Nieri D, Failli M, et al. Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nat Commun. 2020;11:970 pubmed publisher
Fernández Antorán D, Piedrafita G, Murai K, Ong S, Herms A, Frezza C, et al. Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation. Cell Stem Cell. 2019;25:329-341.e6 pubmed publisher
Lewis T, Kwon S, Lee A, SHAW R, Polleux F. MFF-dependent mitochondrial fission regulates presynaptic release and axon branching by limiting axonal mitochondria size. Nat Commun. 2018;9:5008 pubmed publisher
Gutscher M, Pauleau A, Marty L, Brach T, Wabnitz G, Samstag Y, et al. Real-time imaging of the intracellular glutathione redox potential. Nat Methods. 2008;5:553-9 pubmed publisher
product information
Catalog Number :
64977
Product Name :
pLPCX mito Grx1-roGFP2
article :
doi10.1038/nmeth.1212
id10072
pubmed_id18469822
bacterial resistance :
Ampicillin
cloning :
backbonepLPCX
backbone_mutation
backbone_originClontech
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth strain :
Mammalian expression of mitochondrial Grx1-roGFP2 (retroviral vector)
origin :
37
pi :
alt_names
GLRX1_HUMAN
cloning
entrez_gene
aliasesGRX, GRX1
geneGLRX
id2745
genbank_ids
mutationmitochondrial targeting sequence
nameGlutaredoxin-1
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on insert
tagroGFP2
resistance markers :
2341
tags :
Low Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA