This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
ptf-Galectin3
catalog :
64149
citations: 8
Reference
Bhattacharya A, Mukherjee R, Kuncha S, Brunstein M, Rathore R, Junek S, et al. A lysosome membrane regeneration pathway depends on TBC1D15 and autophagic lysosomal reformation proteins. Nat Cell Biol. 2023;25:685-698 pubmed publisher
Gallagher E, Holzbaur E. The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy. Cell Rep. 2023;42:112037 pubmed publisher
Wang S, Jing K, Wu H, Li X, Yang C, Li T, et al. Activation of Transcription Factor EB Alleviates Tubular Epithelial Cell Injury via Restoring Lysosomal Homeostasis in Diabetic Nephropathy. Oxid Med Cell Longev. 2022;2022:2812493 pubmed publisher
Martinelli S, Anderzhanova E, Bajaj T, Wiechmann S, Dethloff F, Weckmann K, et al. Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion. Nat Commun. 2021;12:4643 pubmed publisher
Actis C, Muzio G, Autelli R. Autophagy Triggers Tamoxifen Resistance in Human Breast Cancer Cells by Preventing Drug-Induced Lysosomal Damage. Cancers (Basel). 2021;13: pubmed publisher
Yang C, Chen X, Li Z, Wu H, Jing K, Huang X, et al. SMAD3 promotes autophagy dysregulation by triggering lysosome depletion in tubular epithelial cells in diabetic nephropathy. Autophagy. 2020;:1-20 pubmed publisher
Otomo T, Yoshimori T. Lysophagy: A Method for Monitoring Lysosomal Rupture Followed by Autophagy-Dependent Recovery. Methods Mol Biol. 2017;1594:141-149 pubmed publisher
Maejima I, Takahashi A, Omori H, Kimura T, Takabatake Y, Saitoh T, et al. Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury. EMBO J. 2013;32:2336-47 pubmed publisher
product information
Catalog Number :
64149
Product Name :
ptf-Galectin3
article :
doi10.1038/emboj.2013.171
id9941
pubmed_id23921551
bacterial resistance :
Kanamycin
cloning :
backbonepEGFP-C1+mRFP
backbone_mutation
backbone_originTakara-Clontech
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expression in mammalian cells
origin :
37
pi :
alt_names
LGALS3
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5BglII
promoterCMV
sequencing_primer_3
sequencing_primer_5N/A
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2
geneLGALS3
id3958
genbank_ids
mutation
nameGalectin3
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on insert
tagmRFP
locationN terminal on insert
tagEGFP
resistance markers :
603
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA