This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCDNA3.1-Flag-H2A K118-119R
catalog :
63564
citations: 4
Reference
Benabdallah N, Dalal V, Scott R, Marcous F, Sotiriou A, Kommoss F, et al. Aberrant gene activation in synovial sarcoma relies on SSX specificity and increased PRC1.1 stability. Nat Struct Mol Biol. 2023;30:1640-1652 pubmed publisher
Wohlberedt K, Klusmann I, Derevyanko P, Henningsen K, Choo J, Manzini V, et al. Mdm4 supports DNA replication in a p53-independent fashion. Oncogene. 2020;39:4828-4843 pubmed publisher
Klusmann I, Wohlberedt K, Magerhans A, Teloni F, Korbel J, Altmeyer M, et al. Chromatin modifiers Mdm2 and RNF2 prevent RNA:DNA hybrids that impair DNA replication. Proc Natl Acad Sci U S A. 2018;115:E11311-E11320 pubmed publisher
Mattiroli F, Vissers J, van Dijk W, Ikpa P, Citterio E, Vermeulen W, et al. RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling. Cell. 2012;150:1182-95 pubmed publisher
product information
Catalog Number :
63564
Product Name :
pCDNA3.1-Flag-H2A K118-119R
article :
doi10.1016/j.cell.2012.08.005
id9791
pubmed_id22980979
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expression of human H2A with K118R and K119R tagged with Flag
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRV
cloning_site_5BamHI
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesH2A, H2A-GL101, H2A/q, H2AFQ, HIST2H2AC
geneH2AC20
id8338
genbank_ids
mutationLysine 118 and Lysine 119 are now Arginine
nameH2A
shRNA_sequence
size394
species
9606
Homo sapiens
tags
locationN terminal on insert
tagFlag (MDYKDDDDKVPRIQ)
resistance markers :
2258
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA