Somborac T, Lutfullahoglu Bal G, Fatima K, Vihinen H, Paatero A, Jokitalo E, et al. The subset of peroxisomal tail-anchored proteins do not reach peroxisomes via ER, instead mitochondria can be involved. PLoS ONE. 2023;18:e0295047 pubmed publisher

Tollis P, Vitiello E, Migliaccio F, D Ambra E, Rocchegiani A, Garone M, et al. The long noncoding RNA nHOTAIRM1 is necessary for differentiation and activity of iPSC-derived spinal motor neurons. Cell Death Dis. 2023;14:741 pubmed publisher

Hasan M, Hyodo T, Biswas M, Rahman M, Mihara Y, Karnan S, et al. Flow cytometry-based quantification of genome editing efficiency in human cell lines using the L1CAM gene. PLoS ONE. 2023;18:e0294146 pubmed publisher

Zukher I, Dujardin G, Sousa Lu xed s R, Proudfoot N. Elongation roadblocks mediated by dCas9 across human genes modulate transcription and nascent RNA processing. Nat Struct Mol Biol. 2023;30:1536-1548 pubmed publisher

Yan W, Zhong Y, Hu X, Xu T, Zhang Y, Kales S, et al. Auranofin targets UBA1 and enhances UBA1 activity by facilitating ubiquitin trans-thioesterification to E2 ubiquitin-conjugating enzymes. Nat Commun. 2023;14:4798 pubmed publisher

She X, Wu Q, Rao Z, Song D, Huang C, Feng S, et al. SETDB1 Methylates MCT1 Promoting Tumor Progression by Enhancing the Lactate Shuttle. Adv Sci (Weinh). 2023;10:e2301871 pubmed publisher

Chakraborty P, Deb B, Arige V, Musthafa T, Malik S, Yule D, et al. Regulation of store-operated Ca2+ entry by IP3 receptors independent of their ability to release Ca2. elife. 2023;12: pubmed publisher

Qian Y, Wang J, Wang B, Wang W, Li P, Zhao Z, et al. Systematic fine-mapping and functional studies of prostate cancer risk variants. iScience. 2023;26:106497 pubmed publisher

Stricker S, M xfc ller M, Zimmer K, Jacob R. Altered Posttranslational Modification of Microtubules Contributes to Disturbed Enterocyte Morphology in Celiac Disease. Int J Mol Sci. 2023;24: pubmed publisher

Jones E, Butler M, Trendafilova D, Mendez M, Jernigan L, Gahtan E, et al. In vivo tracking of KCC2b expression during early brain development. J Comp Neurol. 2023;531:48-57 pubmed publisher

Brauer E, Lange T, Keller D, G xf6 rlitz S, Cho S, Keye J, et al. Dissecting the influence of cellular senescence on cell mechanics and extracellular matrix formation in vitro. Aging Cell. 2022;:e13744 pubmed publisher

Fdez E, Madero Pérez J, Lara Ordóñez A, Naaldijk Y, Fasiczka R, Aiastui A, et al. Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement. iScience. 2022;25:104476 pubmed publisher

Endo Y, Groom L, Celik A, Kraeva N, Lee C, Jung S, et al. Variants in ASPH cause exertional heat illness and are associated with malignant hyperthermia susceptibility. Nat Commun. 2022;13:3403 pubmed publisher

Ne E, Crespo R, Izquierdo Lara R, Rao S, Koçer S, Górska A, et al. Catchet-MS identifies IKZF1-targeting thalidomide analogues as novel HIV-1 latency reversal agents. Nucleic Acids Res. 2022;50:5577-5598 pubmed publisher

Guiro J, Fagbemi M, Tellier M, Zaborowska J, Barker S, Fournier M, et al. CAPTURE of the Human U2 snRNA Genes Expands the Repertoire of Associated Factors. Biomolecules. 2022;12: pubmed publisher

Xu W, Liu C, Deng B, Lin P, Sun Z, Liu A, et al. TP53-inducible putative long noncoding RNAs encode functional polypeptides that suppress cell proliferation. Genome Res. 2022;32:1026-1041 pubmed publisher

Smolin E, Buyan A, Lyabin D, Kulakovskiy I, Eliseeva I. RNA-Seq data of ALKBH5 and FTO double knockout HEK293T human cells. Data Brief. 2022;42:108187 pubmed publisher

Chen Q, Bates A, Hanquier J, Simpson E, Rusch D, Podicheti R, et al. Structural and genome-wide analyses suggest that transposon-derived protein SETMAR alters transcription and splicing. J Biol Chem. 2022;298:101894 pubmed publisher

Lee D, Jeong Y, Won J, Sim H, Park Y, Jin H. PBK/TOPK Is a Favorable Prognostic Biomarker Correlated with Antitumor Immunity in Colon Cancers. Biomedicines. 2022;10: pubmed publisher

Zheng D, Wang X, Zhang Z, Li E, Yeung C, Borkar R, et al. Engineering of human mesenchymal stem cells resistant to multiple natural killer subtypes. Int J Biol Sci. 2022;18:426-440 pubmed publisher

Kawahara R, Simizu S. ErbB4-mediated regulation of vasculogenic mimicry capability in breast cancer cells. Cancer Sci. 2022;113:950-959 pubmed publisher

Rahman M, Hyodo T, Karnan S, Ota A, Hasan M, Mihara Y, et al. Experimental strategies to achieve efficient targeted knock-in via tandem paired nicking. Sci Rep. 2021;11:22627 pubmed publisher

Rahman M, Hyodo T, Hasan M, Mihara Y, Karnan S, Ota A, et al. Flow cytometry-based quantification of targeted knock-in events in human cell lines using a GPI-anchor biosynthesis gene PIGP. Biosci Rep. 2021;41: pubmed publisher

Dong T, Tejwani L, Jung Y, Kokubu H, Luttik K, Driessen T, et al. Microglia regulate brain progranulin levels through the endocytosis/lysosomal pathway. JCI Insight. 2021;6: pubmed publisher

Gunkel P, Iino H, Krull S, Cordes V. ZC3HC1 Is a Novel Inherent Component of the Nuclear Basket, Resident in a State of Reciprocal Dependence with TPR. Cells. 2021;10: pubmed publisher

Canals I, Ahlenius H. CRISPR/Cas9 Genome Engineering in Human Pluripotent Stem Cells for Modeling of Neurological Disorders. Methods Mol Biol. 2021;2352:237-251 pubmed publisher

Prokhorova E, Zobel F, Smith R, Zentout S, Gibbs Seymour I, Schützenhofer K, et al. Serine-linked PARP1 auto-modification controls PARP inhibitor response. Nat Commun. 2021;12:4055 pubmed publisher

Velichko A, Ovsyannikova N, Petrova N, Luzhin A, Vorobjeva M, Gavrikov A, et al. Treacle and TOPBP1 control replication stress response in the nucleolus. J Cell Biol. 2021;220: pubmed publisher

Cretin E, Lopes P, Vimont E, Tatsuta T, Langer T, Gazi A, et al. High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts. EMBO Mol Med. 2021;13:e13579 pubmed publisher

Mori K, Suzuki T, Miura K, Dohmae N, Simizu S. Involvement of LH3 and GLT25D1 for glucosyl-galactosyl-hydroxylation on non-collagen-like domain of FGL1. Biochem Biophys Res Commun. 2021;560:93-98 pubmed publisher

Rice S, Roberts J, Tselepi M, Brumwell A, Falk J, Steven C, et al. Genetic and Epigenetic Fine-Tuning of TGFB1 Expression Within the Human Osteoarthritic Joint. Arthritis Rheumatol. 2021;: pubmed publisher

Sayedyahossein S, Huang K, Li Z, Zhang C, Kozlov A, Johnston D, et al. Pannexin 1 binds β-catenin to modulate melanoma cell growth and metabolism. J Biol Chem. 2021;296:100478 pubmed publisher

Müller M, Ringer K, Hub F, Kamm N, Worzfeld T, Jacob R. TTL-Expression Modulates Epithelial Morphogenesis. Front Cell Dev Biol. 2021;9:635723 pubmed publisher

Tang Y, Liao S, Liu G, Xiong X, Liu H, Li F, et al. Advanced single-cell pooled CRISPR screening identifies C19orf53 required for cell proliferation based on mTORC1 regulators. Cell Biol Toxicol. 2021;: pubmed publisher

Julku U, Jäntti M, Svarcbahs R, Myöhänen T. Prolyl Oligopeptidase Regulates Dopamine Transporter Oligomerization and Phosphorylation in a PKC- and ERK-Independent Manner. Int J Mol Sci. 2021;22: pubmed publisher

Zong H, Hazelbaker M, Moe C, Ems McClung S, Hu K, Walczak C. Spatial Regulation of MCAK Promotes Cell Polarization and Focal Adhesion Turnover to Drive Robust Cell Migration. Mol Biol Cell. 2021;:mbcE20050301 pubmed publisher

Adhikari A, Kim W, Davie J. Myogenin is required for assembly of the transcription machinery on muscle genes during skeletal muscle differentiation. PLoS ONE. 2021;16:e0245618 pubmed publisher

Nouri Nejad D, O Donnell B, Patil C, Sanchez Pupo R, Johnston D, Sayedyahossein S, et al. Pannexin 1 mutation found in melanoma tumour reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein. Mol Biol Cell. 2021;:mbcE19100585 pubmed publisher

Kato M, Abdollahi M, Tunduguru R, Tsark W, Chen Z, Wu X, et al. miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1. Commun Biol. 2021;4:30 pubmed publisher

Ramsay E, Abascal Palacios G, Daiß J, King H, Gouge J, Pilsl M, et al. Structure of human RNA polymerase III. Nat Commun. 2020;11:6409 pubmed publisher

Witte K, Slotta C, Lütkemeyer M, Kitke A, Coras R, Simon M, et al. PLEKHG5 regulates autophagy, survival and MGMT expression in U251-MG glioblastoma cells. Sci Rep. 2020;10:21858 pubmed publisher

Peng T, Zhai Y, Atlasi Y, ter Huurne M, Marks H, Stunnenberg H, et al. STARR-seq identifies active, chromatin-masked, and dormant enhancers in pluripotent mouse embryonic stem cells. Genome Biol. 2020;21:243 pubmed publisher

Zhao T, Zhang Akiyama Q. Deficiency of Grx1 leads to high sensitivity of HeLaS3 cells to oxidative stress via excessive accumulation of intracellular oxidants including ROS. Free Radic Res. 2020;54:585-605 pubmed publisher

Wang X, Lu M, Tian X, Ren Y, Li Y, Xiang M, et al. Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey. Stem Cell Res Ther. 2020;11:334 pubmed publisher

Barnard K, Wasik B, LaClair J, Buchholz D, Weichert W, Alford Lawrence B, et al. Expression of 9-O- and 7,9-O-Acetyl Modified Sialic Acid in Cells and Their Effects on Influenza Viruses. MBio. 2019;10: pubmed publisher

Serizawa T, Isotani A, Matsumura T, Nakanishi K, Nonaka S, Shibata S, et al. Developmental analyses of mouse embryos and adults using a non-overlapping tracing system for all three germ layers. Development. 2019;146: pubmed publisher

Chen J, Cao Y, Markelc B, Kaeppler J, Vermeer J, Muschel R. Type I IFN protects cancer cells from CD8+ T cell-mediated cytotoxicity after radiation. J Clin Invest. 2019;129:4224-4238 pubmed publisher

Esteve J, Blouin J, Lalanne M, Azzi Martin L, Dubus P, Bidet A, et al. Targeted gene therapy in human-induced pluripotent stem cells from a patient with primary hyperoxaluria type 1 using CRISPR/Cas9 technology. Biochem Biophys Res Commun. 2019;517:677-683 pubmed publisher

Ellefsen K, Holt J, Chang A, Nourse J, Arulmoli J, Mekhdjian A, et al. Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca2+ flickers. Commun Biol. 2019;2:298 pubmed publisher

Turco E, Witt M, Abert C, Bock Bierbaum T, Su M, Trapannone R, et al. FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates. Mol Cell. 2019;74:330-346.e11 pubmed publisher

Kwiatkowski S, Seliga A, Vertommen D, Terreri M, Ishikawa T, Grabowska I, et al. SETD3 protein is the actin-specific histidine N-methyltransferase. elife. 2018;7: pubmed publisher

Gontan C, Mira Bontenbal H, Magaraki A, Dupont C, Barakat T, Rentmeester E, et al. REX1 is the critical target of RNF12 in imprinted X chromosome inactivation in mice. Nat Commun. 2018;9:4752 pubmed publisher

Yang J, Park J, Zheng D, Xu R. Universal Corneal Epithelial-Like Cells Derived from Human Embryonic Stem Cells for Cellularization of a Corneal Scaffold. Transl Vis Sci Technol. 2018;7:23 pubmed publisher

Ringer K, Riehl J, Müller M, Dewes J, Hoff F, Jacob R. The large GTPase Mx1 binds Kif5B for cargo transport along microtubules. Traffic. 2018;19:947-964 pubmed publisher

Martin Gonzalez J, Baudet A, Abelechian S, Bonderup K, D Altri T, Porse B, et al. A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines. Genesis. 2018;56:e23238 pubmed publisher

Kawahara R, Niwa Y, Simizu S. Integrin β1 is an essential factor in vasculogenic mimicry of human cancer cells. Cancer Sci. 2018;109:2490-2496 pubmed publisher

Künzel U, Grieve A, Meng Y, Sieber B, Cowley S, Freeman M. FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex. elife. 2018;7: pubmed publisher

Hönig E, Ringer K, Dewes J, von Mach T, Kamm N, Kreitzer G, et al. Galectin-3 modulates the polarized surface delivery of ?1-integrin in epithelial cells. J Cell Sci. 2018;131: pubmed publisher

Slotta C, Storm J, Pfisterer N, Henkel E, Kleinwächter S, Pieper M, et al. IKK1/2 protect human cells from TNF-mediated RIPK1-dependent apoptosis in an NF-κB-independent manner. Biochim Biophys Acta Mol Cell Res. 2018;1865:1025-1033 pubmed publisher

Corsini N, Peer A, Moeseneder P, Roiuk M, Burkard T, Theussl H, et al. Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation. Cell Stem Cell. 2018;22:543-558.e12 pubmed publisher

Chen J, Markelc B, Kaeppler J, Ogundipe V, Cao Y, McKenna W, et al. STING-Dependent Interferon-λ1 Induction in HT29 Cells, a Human Colorectal Cancer Cell Line, After Gamma-Radiation. Int J Radiat Oncol Biol Phys. 2018;101:97-106 pubmed publisher

Virant D, Traenkle B, Maier J, Kaiser P, Bodenhöfer M, Schmees C, et al. A peptide tag-specific nanobody enables high-quality labeling for dSTORM imaging. Nat Commun. 2018;9:930 pubmed publisher

Olley G, Ansari M, Bengani H, Grimes G, Rhodes J, von Kriegsheim A, et al. BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange-like syndrome. Nat Genet. 2018;50:329-332 pubmed publisher

Svarcbahs R, Julku U, Norrbacka S, Myöhänen T. Removal of prolyl oligopeptidase reduces alpha-synuclein toxicity in cells and in vivo. Sci Rep. 2018;8:1552 pubmed publisher

Chen C, Zeldich E, Li Y, Yuste A, Abraham C. Activation of the Anti-Aging and Cognition-Enhancing Gene Klotho by CRISPR-dCas9 Transcriptional Effector Complex. J Mol Neurosci. 2018;64:175-184 pubmed publisher

Zaffagnini G, Savova A, Danieli A, Romanov J, Tremel S, Ebner M, et al. p62 filaments capture and present ubiquitinated cargos for autophagy. EMBO J. 2018;37: pubmed publisher

Kim J, Sturgill D, Sebastian R, Khurana S, Tran A, Edwards G, et al. Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions. Mol Cell. 2018;69:36-47.e7 pubmed publisher

Adikusuma F, Pfitzner C, Thomas P. Versatile single-step-assembly CRISPR/Cas9 vectors for dual gRNA expression. PLoS ONE. 2017;12:e0187236 pubmed publisher

Vanli G, Cuesta Marbán A, Widmann C. Evaluation and validation of commercial antibodies for the detection of Shb. PLoS ONE. 2017;12:e0188311 pubmed publisher

Moder M, Velimezi G, Owusu M, Mazouzi A, Wiedner M, Ferreira da Silva J, et al. Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia. Nat Commun. 2017;8:1238 pubmed publisher

Castrogiovanni C, Waterschoot B, De Backer O, Dumont P. Serine 392 phosphorylation modulates p53 mitochondrial translocation and transcription-independent apoptosis. Cell Death Differ. 2017;: pubmed publisher

Yamamoto Y, Makiyama T, Harita T, Sasaki K, Wuriyanghai Y, Hayano M, et al. Allele-specific ablation rescues electrophysiological abnormalities in a human iPS cell model of long-QT syndrome with a CALM2 mutation. Hum Mol Genet. 2017;26:1670-1677 pubmed publisher

Lees J, Messa M, Sun E, Wheeler H, Torta F, Wenk M, et al. Lipid transport by TMEM24 at ER-plasma membrane contacts regulates pulsatile insulin secretion. Science. 2017;355: pubmed publisher

Hu T, Zhu X, Pi W, Yu M, Shi H, Tuan D. Hypermethylated LTR retrotransposon exhibits enhancer activity. Epigenetics. 2017;12:226-237 pubmed publisher

Hu T, Pi W, Zhu X, Yu M, Ha H, Shi H, et al. Long non-coding RNAs transcribed by ERV-9 LTR retrotransposon act in cis to modulate long-range LTR enhancer function. Nucleic Acids Res. 2017;45:4479-4492 pubmed publisher

Bara A, Messana A, Herring A, Hazelbaker D, Eggan K, Barrett L. Generation of a TLE3 heterozygous knockout human embryonic stem cell line using CRISPR-Cas9. Stem Cell Res. 2016;17:441-443 pubmed publisher

Santos D, Kiskinis E, Eggan K, Merkle F. Comprehensive Protocols for CRISPR/Cas9-based Gene Editing in Human Pluripotent Stem Cells. Curr Protoc Stem Cell Biol. 2016;38:5B.6.1-5B.6.60 pubmed publisher

Sayedyahossein S, Li Z, Hedman A, Morgan C, Sacks D. IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity. J Biol Chem. 2016;291:19261-73 pubmed publisher

Gibbs Seymour I, Fontana P, Rack J, Ahel I. HPF1/C4orf27 Is a PARP-1-Interacting Protein that Regulates PARP-1 ADP-Ribosylation Activity. Mol Cell. 2016;62:432-442 pubmed publisher

Ran F, Hsu P, Wright J, Agarwala V, Scott D, Zhang F. Genome engineering using the CRISPR-Cas9 system. Nat Protoc. 2013;8:2281-2308 pubmed publisher