This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Mucolipin1-pEGFP C3
catalog :
62960
citations: 4
Reference
Wrobel M, Cendrowski J, Szymańska E, Grębowicz Maciukiewicz M, Budick Harmelin N, Macias M, et al. ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway. Life Sci Alliance. 2022;5: pubmed publisher
Lie P, Yang D, Stavrides P, Goulbourne C, Zheng P, Mohan P, et al. Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons. Cell Rep. 2021;35:109034 pubmed publisher
Qi J, Xing Y, Liu Y, Wang M, Wei X, Sui Z, et al. MCOLN1/TRPML1 finely controls oncogenic autophagy in cancer by mediating zinc influx. Autophagy. 2021;:1-22 pubmed publisher
Pryor P, Reimann F, Gribble F, Luzio J. Mucolipin-1 is a lysosomal membrane protein required for intracellular lactosylceramide traffic. Traffic. 2006;7:1388-98 pubmed
product information
Catalog Number :
62960
Product Name :
Mucolipin1-pEGFP C3
article :
doi10.1111/j.1600-0854.2006.00475.x
id9729
pubmed_id16978393
bacterial resistance :
Kanamycin
cloning :
backbonepEGFP C3
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
full length human Mucolipin-1 cloned into pEGFP C3
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3KpnI
cloning_site_5XhoI
promoterCMV
sequencing_primer_35 ACAAACCACAACTAGAATGCAG 3
sequencing_primer_55 CCGACAACCACTACCTGAGC 3
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMG-2, ML1, ML4, MLIV, MST080, MSTP080, TRP-ML1, TRPM-L1, TRPML1
geneMCOLN1
id57192
genbank_ids
NM_020533.2
Q9GZU1
mutationMucolipin-1 has 1 silent mutation compared to the coding sequence of NM_020533.2 N328 AAT instead of AAC
nameMucolipin-1
shRNA_sequence
size1761
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagEGFP
resistance markers :
2251
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA