This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Rtn4a-GFP
catalog :
61807
citations: 10
Reference
Wang B, Zhao Z, Xiong M, Yan R, Xu K. The endoplasmic reticulum adopts two distinct tubule forms. Proc Natl Acad Sci U S A. 2022;119:e2117559119 pubmed publisher
Parlakgul G, Arruda A, Pang S, Cagampan E, Min N, Güney E, et al. Regulation of liver subcellular architecture controls metabolic homeostasis. Nature. 2022;603:736-742 pubmed publisher
Özkan N, Koppers M, van Soest I, van Harten A, Jurriens D, Liv N, et al. ER - lysosome contacts at a pre-axonal region regulate axonal lysosome availability. Nat Commun. 2021;12:4493 pubmed publisher
Joshi A, Ragusa J, Prinz W, Cohen S. Multiple C2 domain-containing transmembrane proteins promote lipid droplet biogenesis and growth at specialized endoplasmic reticulum subdomains. Mol Biol Cell. 2021;32:1147-1157 pubmed publisher
Adachi Y, Kato T, Yamada T, Murata D, Arai K, Stahelin R, et al. Drp1 Tubulates the ER in a GTPase-Independent Manner. Mol Cell. 2020;80:621-632.e6 pubmed publisher
Jiang X, Jia X, Sun J, Qi C, Lu L, Wang Y, et al. Overexpressed coiled-coil domain containing protein 8 (CCDC8) mediates newly synthesized HIV-1 Gag lysosomal degradation. Sci Rep. 2020;10:11416 pubmed publisher
Pan X, Cao Y, Stucchi R, Hooikaas P, Portegies S, Will L, et al. MAP7D2 Localizes to the Proximal Axon and Locally Promotes Kinesin-1-Mediated Cargo Transport into the Axon. Cell Rep. 2019;26:1988-1999.e6 pubmed publisher
Farías G, Fréal A, Tortosa E, Stucchi R, Pan X, Portegies S, et al. Feedback-Driven Mechanisms between Microtubules and the Endoplasmic Reticulum Instruct Neuronal Polarity. Neuron. 2019;102:184-201.e8 pubmed publisher
Pathak G, Shah R, Kennedy B, Murphy J, Clements D, Konda P, et al. RTN4 Knockdown Dysregulates the AKT Pathway, Destabilizes the Cytoskeleton, and Enhances Paclitaxel-Induced Cytotoxicity in Cancers. Mol Ther. 2018;26:2019-2033 pubmed publisher
Shibata Y, Voss C, Rist J, Hu J, Rapoport T, Prinz W, et al. The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum. J Biol Chem. 2008;283:18892-904 pubmed publisher
product information
Catalog Number :
61807
Product Name :
Rtn4a-GFP
article :
doi10.1074/jbc.M800986200
id3776
pubmed_id18442980
bacterial resistance :
Kanamycin
cloning :
backbonepAcGFP1-N1
backbone_mutationNone
backbone_originClontech
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Human Rtn4a fluorescently tagged with GFP on the C-terminus for mammalian expression
origin :
37
pi :
alt_names
NOGO-A
cloning
clone_methodRestriction Enzyme
cloning_site_3KpnI
cloning_site_5XhoI
promoterCMV
sequencing_primer_3None
sequencing_primer_5None
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesASY, NI220/250, NOGO, NSP, NSP-CL, Nbla00271, Nbla10545, RTN-X, RTN4-A, RTN4-B1, RTN4-B2, RTN4-C
geneRTN4
id57142
genbank_ids
NM_020532.4
mutationRtn4a Stop Codon removed
nameRtn4a
shRNA_sequence
size3579
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagGFP
resistance markers :
1740
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA