This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
TetO-FUW-NICD
catalog :
61540
citations: 9
Reference
Messerschmidt V, Chintapula U, Bonetesta F, Laboy Segarra S, Naderi A, Nguyen K, et al. In vivo Evaluation of Non-viral NICD Plasmid-Loaded PLGA Nanoparticles in Developing Zebrafish to Improve Cardiac Functions. Front Physiol. 2022;13:819767 pubmed publisher
Messerschmidt V, Chintapula U, Kuriakose A, Laboy S, Truong T, Kydd L, et al. Notch Intracellular Domain Plasmid Delivery via Poly(Lactic-Co-Glycolic Acid) Nanoparticles to Upregulate Notch Pathway Molecules. Front Cardiovasc Med. 2021;8:707897 pubmed publisher
Chen H, Poran A, Unni A, Huang S, Elemento O, Snoeck H, et al. Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells. J Exp Med. 2019;216:674-687 pubmed publisher
Augert A, Eastwood E, Ibrahim A, Wu N, Grunblatt E, Basom R, et al. Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition. Sci Signal. 2019;12: pubmed publisher
Meng Y, Liang J, Wu C, Xu J, Zeng D, Yu X, et al. Monocytes/Macrophages promote vascular CXCR4 expression via the ERK pathway in hepatocellular carcinoma. Oncoimmunology. 2018;7:e1408745 pubmed publisher
Oh S, Kessler J. Design, Assembly, Production, and Transfection of Synthetic Modified mRNA. Methods. 2018;133:29-43 pubmed publisher
Guo Y, Zhang K, Cheng C, Ji Z, Wang X, Wang M, et al. Numb-/low Enriches a Castration-Resistant Prostate Cancer Cell Subpopulation Associated with Enhanced Notch and Hedgehog Signaling. Clin Cancer Res. 2017;23:6744-6756 pubmed publisher
Lee B, Lee T, Shim J. Emerin suppresses Notch signaling by restricting the Notch intracellular domain to the nuclear membrane. Biochim Biophys Acta Mol Cell Res. 2017;1864:303-313 pubmed publisher
Cassady J, D Alessio A, Sarkar S, Dani V, Fan Z, Ganz K, et al. Direct lineage conversion of adult mouse liver cells and B lymphocytes to neural stem cells. Stem Cell Reports. 2014;3:948-56 pubmed publisher
product information
Catalog Number :
61540
Product Name :
TetO-FUW-NICD
article :
doi10.1016/j.stemcr.2014.10.001
id9446
pubmed_id25454632
bacterial resistance :
Ampicillin
cloning :
backboneTetO-FUW
backbone_mutation
backbone_origin
backbone_size8376
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
growth strain :
Expresses NOTCH-ICD in mammalian cells
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3TTCCGCCGTGGCAATAGGGA
sequencing_primer_5AAGACCACCGCACAGCAAGC
site_3_destroyed1
site_5_destroyed1
entrez_gene
aliasesAOS5, AOVD1, TAN1, hN1
geneNOTCH1
id4851
genbank_ids
mutationNOTCH intracellular domain (aa1761-2555); A1943S mutation compared to reference sequence NM_017617.3
nameNOTCH-ICD
shRNA_sequence
size2460
species
9606
Homo sapiens
tags
resistance markers :
227
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA