Reference |
---|
Su Tobon Q, Fan J, Feeney K, Ren H, Autissier P, Wang P, et al. CRISPR-Hybrid: A CRISPR-Mediated Intracellular Directed Evolution Platform for RNA Aptamers. bioRxiv. 2023;: pubmed publisher
|
Sgro A, Cursons J, Waryah C, Woodward E, Foroutan M, Lyu R, et al. Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma. Clin Epigenetics. 2023;15:73 pubmed publisher
|
Huang W, Sakuma S, Tottori N, Sugano S, Yamanishi Y. Viscosity-aided electromechanical poration of cells for transfecting molecules. Lab Chip. 2022;22:4276-4291 pubmed publisher
|
Chen W, Gaidukov L, Lai Y, Wu M, Cao J, Gutbrod M, et al. A synthetic transcription platform for programmable gene expression in mammalian cells. Nat Commun. 2022;13:6167 pubmed publisher
|
Chan W, Coughlan H, Chen Y, Keenan C, Smyth G, Perkins A, et al. Activation of stably silenced genes by recruitment of a synthetic de-methylating module. Nat Commun. 2022;13:5582 pubmed publisher
|
Leung H, Foo G, VanDongen A. Arc Regulates Transcription of Genes for Plasticity, Excitability and Alzheimer's Disease. Biomedicines. 2022;10: pubmed publisher
|
Wang J, Wang A, Tian K, Hua X, Zhang B, Zheng Y, et al. A Ctnnb1 enhancer regulates neocortical neurogenesis by controlling the abundance of intermediate progenitors. Cell Discov. 2022;8:74 pubmed publisher
|
Wang K, Escobar M, Li J, Mahata B, Goell J, Shah S, et al. Systematic comparison of CRISPR-based transcriptional activators uncovers gene-regulatory features of enhancer-promoter interactions. Nucleic Acids Res. 2022;50:7842-7855 pubmed publisher
|
Ma H, de Zwaan E, Guo Y, Cejas P, Thiru P, van de Bunt M, et al. The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes. Cell Stem Cell. 2022;29:795-809.e11 pubmed publisher
|
Wang C, Qu Y, Cheng J, Hughes N, Zhang Q, Wang M, et al. dCas9-based gene editing for cleavage-free genomic knock-in of long sequences. Nat Cell Biol. 2022;24:268-278 pubmed publisher
|
Fennell K, Vassiliadis D, Lam E, Martelotto L, Balic J, Hollizeck S, et al. Non-genetic determinants of malignant clonal fitness at single-cell resolution. Nature. 2022;601:125-131 pubmed publisher
|
Wang C, Xia Q, Zhang Q, Qu Y, Su S, Cheng J, et al. CRISPR-Cas12a System With Synergistic Phage Recombination Proteins for Multiplex Precision Editing in Human Cells. Front Cell Dev Biol. 2021;9:719705 pubmed publisher
|
Zeng J, Xu H, Huang C, Sun Y, Xiao H, Yu G, et al. CD46 splice variant enhances translation of specific mRNAs linked to an aggressive tumor cell phenotype in bladder cancer. Mol Ther Nucleic Acids. 2021;24:140-153 pubmed publisher
|
Zhang X, Lv S, Luo Z, Hu Y, Peng X, Lv J, et al. MiniCAFE, a CRISPR/Cas9-based compact and potent transcriptional activator, elicits gene expression in vivo. Nucleic Acids Res. 2021;49:4171-4185 pubmed publisher
|
Lu X, Chen X, Forney C, Donmez O, Miller D, Parameswaran S, et al. Global discovery of lupus genetic risk variant allelic enhancer activity. Nat Commun. 2021;12:1611 pubmed publisher
|
Wang C, Cheng J, Zhang Q, Hughes N, Xia Q, Winslow M, et al. Microbial single-strand annealing proteins enable CRISPR gene-editing tools with improved knock-in efficiencies and reduced off-target effects. Nucleic Acids Res. 2021;49:e36 pubmed publisher
|
Hamann M, Ehmele P, Verdikt R, Bialek Waldmann J, Virdi S, Gunther T, et al. Transcriptional behavior of the HIV-1 promoter in context of the BACH2 prominent proviral integration gene. Virus Res. 2021;293:198260 pubmed publisher
|
Velazquez J, LeGraw R, Moghadam F, Tan Y, Kilbourne J, Maggiore J, et al. Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids. Cell Syst. 2021;12:41-55.e11 pubmed publisher
|
Dai Y, Luo W, Yue X, Ma W, Wang J, Chang J. Identification and characterization of a new isoform of small GTPase RhoE. Commun Biol. 2020;3:572 pubmed publisher
|
Ruan X, Li P, Ma Y, Jiang C, Chen Y, Shi Y, et al. Identification of human long noncoding RNAs associated with nonalcoholic fatty liver disease and metabolic homeostasis. J Clin Invest. 2021;131: pubmed publisher
|
Ferry Q, Fulga T. Controlling the Activity of CRISPR Transcriptional Regulators with Inducible sgRNAs. Methods Mol Biol. 2021;2162:153-184 pubmed publisher
|
Hsu M, Liao H, Truong V, Huang K, Yu F, Chen H, et al. CRISPR-based Activation of Endogenous Neurotrophic Genes in Adipose Stem Cell Sheets to Stimulate Peripheral Nerve Regeneration. Theranostics. 2019;9:6099-6111 pubmed publisher
|
Cheng T, Li S, Yuan B, Wang X, Zhou W, Qiu Z. Expanding C-T base editing toolkit with diversified cytidine deaminases. Nat Commun. 2019;10:3612 pubmed publisher
|
Kunii A, Hara Y, Takenaga M, Hattori N, Fukazawa T, Ushijima T, et al. Three-Component Repurposed Technology for Enhanced Expression: Highly Accumulable Transcriptional Activators via Branched Tag Arrays. CRISPR J. 2018;1:337-347 pubmed publisher
|
Yamazaki T, Fujikawa C, Kubota A, Takahashi A, Hirose T. CRISPRa-mediated NEAT1 lncRNA upregulation induces formation of intact paraspeckles. Biochem Biophys Res Commun. 2018;504:218-224 pubmed publisher
|
Nakade S, Mochida K, Kunii A, Nakamae K, Aida T, Tanaka K, et al. Biased genome editing using the local accumulation of DSB repair molecules system. Nat Commun. 2018;9:3270 pubmed publisher
|
Zhao Z, Sentürk N, Song C, Grummt I. lncRNA PAPAS tethered to the rDNA enhancer recruits hypophosphorylated CHD4/NuRD to repress rRNA synthesis at elevated temperatures. Genes Dev. 2018;32:836-848 pubmed publisher
|
Lange U, Bialek J, Walther T, Hauber J. Pinpointing recurrent proviral integration sites in new models for latent HIV-1 infection. Virus Res. 2018;249:69-75 pubmed publisher
|
Williams R, Senanayake U, Artibani M, Taylor G, Wells D, Ahmed A, et al. Genome and epigenome engineering CRISPR toolkit for in vivo modulation of cis-regulatory interactions and gene expression in the chicken embryo. Development. 2018;145: pubmed publisher
|
Chen C, Zeldich E, Li Y, Yuste A, Abraham C. Activation of the Anti-Aging and Cognition-Enhancing Gene Klotho by CRISPR-dCas9 Transcriptional Effector Complex. J Mol Neurosci. 2018;64:175-184 pubmed publisher
|
Liao H, Hatanaka F, Araoka T, Reddy P, Wu M, Sui Y, et al. In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation. Cell. 2017;171:1495-1507.e15 pubmed publisher
|
Kulcsár P, Tálas A, Huszár K, Ligeti Z, Tóth E, Weinhardt N, et al. Crossing enhanced and high fidelity SpCas9 nucleases to optimize specificity and cleavage. Genome Biol. 2017;18:190 pubmed publisher
|
Nihongaki Y, Furuhata Y, Otabe T, Hasegawa S, Yoshimoto K, Sato M. CRISPR-Cas9-based photoactivatable transcription systems to induce neuronal differentiation. Nat Methods. 2017;14:963-966 pubmed publisher
|
Ferry Q, Lyutova R, Fulga T. Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs. Nat Commun. 2017;8:14633 pubmed publisher
|
Hu L, Yu Y, Huang H, Fan H, Hu L, Yin C, et al. Epigenetic Regulation of Interleukin 6 by Histone Acetylation in Macrophages and Its Role in Paraquat-Induced Pulmonary Fibrosis. Front Immunol. 2016;7:696 pubmed publisher
|
Chen F, Li X, Aquadro E, Haigh S, Zhou J, Stepp D, et al. Inhibition of histone deacetylase reduces transcription of NADPH oxidases and ROS production and ameliorates pulmonary arterial hypertension. Free Radic Biol Med. 2016;99:167-178 pubmed publisher
|
Bialek J, Dunay G, Voges M, Schäfer C, Spohn M, Stucka R, et al. Targeted HIV-1 Latency Reversal Using CRISPR/Cas9-Derived Transcriptional Activator Systems. PLoS ONE. 2016;11:e0158294 pubmed publisher
|
Kaczmarczyk L, Mende Y, Zevnik B, Jackson W. Manipulating the Prion Protein Gene Sequence and Expression Levels with CRISPR/Cas9. PLoS ONE. 2016;11:e0154604 pubmed publisher
|
Konermann S, Brigham M, Trevino A, Joung J, Abudayyeh O, Bárcena C, et al. Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. Nature. 2015;517:583-8 pubmed publisher
|