pLentiX2-PURO-shLKB1-Hu | Addgene 61242 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pLentiX2-PURO-shLKB1-Hu

catalog :

61242

citations: 3

Reference
Lee H, Cai F, Kelekar N, Velupally N, Kim J. Targeting PGM3 as a Novel Therapeutic Strategy in KRAS/LKB1 Co-Mutant Lung Cancer. Cells. 2022;11: pubmed publisher
Kim J, Lee H, Cai F, Ko B, Yang C, Lieu E, et al. The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer. Nat Metab. 2020;2:1401-1412 pubmed publisher
Goodwin J, Svensson R, Lou H, Winslow M, Turk B, Shaw R. An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential. Mol Cell. 2014;55:436-50 pubmed publisher

product information

Catalog Number :

61242

Product Name :

pLentiX2-PURO-shLKB1-Hu

article :

doi	10.1016/j.molcel.2014.06.021
id	9315
pubmed_id	25042806

bacterial resistance :

Ampicillin

cloning :

backbone

pLentiX2-PURO

backbone_mutation

backbone_origin

Eric Campeau

backbone_size

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Lentiviral

growth strain :

Lentivirus expressing shRNA to human LKB1

origin :

pi :

alt_names

STK11

cloning

clone_method	Gateway Cloning
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5	H1
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	LKB1, PJS, hLKB1
gene	STK11
id	6794

genbank_ids

mutation

name

LKB1

shRNA_sequence

CGAAGAGAAGCAGAAAATG

size

species

9606

Homo sapiens