This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
p3XFlag-CAPN1
catalog :
60941
citations: 7
Reference
Tammineni E, Figueroa L, Manno C, Varma D, Kraeva N, Ibarra C, et al. Muscle calcium stress cleaves junctophilin1, unleashing a gene regulatory program predicted to correct glucose dysregulation. elife. 2023;12: pubmed publisher
Gal J, Bondada V, Mashburn C, Rodgers D, Croall D, Geddes J. S-acylation regulates the membrane association and activity of Calpain-5. Biochim Biophys Acta Mol Cell Res. 2022;1869:119298 pubmed publisher
Nowak K, Taubert R, Haberecht S, Venz S, Krüger E. Inhibition of calpain-1 stabilizes TCF11/Nrf1 but does not affect its activation in response to proteasome inhibition. Biosci Rep. 2018;38: pubmed publisher
Jacquemet G, Baghirov H, Georgiadou M, Sihto H, Peuhu E, Cettour Janet P, et al. L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling. Nat Commun. 2016;7:13297 pubmed publisher
Zhang Y, Li Q, Youn J, Cai H. Protein Phosphotyrosine Phosphatase 1B (PTP1B) in Calpain-dependent Feedback Regulation of Vascular Endothelial Growth Factor Receptor (VEGFR2) in Endothelial Cells: IMPLICATIONS IN VEGF-DEPENDENT ANGIOGENESIS AND DIABETIC WOUND HEALING. J Biol Chem. 2017;292:407-416 pubmed publisher
Coly P, Perzo N, Le Joncour V, Lecointre C, Schouft M, Desrues L, et al. Chemotactic G protein-coupled receptors control cell migration by repressing autophagosome biogenesis. Autophagy. 2016;12:2344-2362 pubmed
Wang Y, Zhang Y. Regulation of TET protein stability by calpains. Cell Rep. 2014;6:278-84 pubmed publisher
product information
Catalog Number :
60941
Product Name :
p3XFlag-CAPN1
article :
doi10.1016/j.celrep.2013.12.031
id9251
pubmed_id24412366
bacterial resistance :
Ampicillin
cloning :
backbonep3xFlag-CMV-14
backbone_mutation
backbone_originsigma
backbone_size6310
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expresses calpain1 in mammalian cells
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3BamH1
cloning_site_5EcoRI
promoterCMV
sequencing_primer_3
sequencing_primer_5CMV pro
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCANP, CANP1, CANPL1, SPG76, muCANP, muCL
geneCAPN1
id823
genbank_ids
mutation
nameCalpain1
shRNA_sequence
size2145
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagflag
resistance markers :
2065
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA