This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
GFP-APPL1- PTB
catalog :
59768
citations: 2
Reference
York H, Patil A, Moorthi U, Kaur A, Bhowmik A, Hyde G, et al. Rapid whole cell imaging reveals a calcium-APPL1-dynein nexus that regulates cohort trafficking of stimulated EGF receptors. Commun Biol. 2021;4:224 pubmed publisher
Broussard J, Lin W, Majumdar D, Anderson B, Eason B, Brown C, et al. The endosomal adaptor protein APPL1 impairs the turnover of leading edge adhesions to regulate cell migration. Mol Biol Cell. 2012;23:1486-99 pubmed publisher
product information
Catalog Number :
59768
Product Name :
GFP-APPL1- PTB
article :
doi10.1091/mbc.E11-02-0124
id8963
pubmed_id22379109
bacterial resistance :
Kanamycin
cloning :
backbonepIRES2
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expresses APPL1 with PTB domain deleted
origin :
37
pi :
alt_names
cloning
clone_methodUnknown
cloning_site_3
cloning_site_5
promoterCMV
sequencing_primer_3taggtacccaggctgatcttcacacac
sequencing_primer_5tcgaattcggcttatgccgg
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAPPL, DIP13alpha, MODY14
geneAPPL1
id26060
genbank_ids
NM_012096.2
mutationdeleted amino acids 467-709
nameAPPL1
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on insert
tagEGFP
resistance markers :
2063
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA