This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pBMN-mCherry-Parkin
catalog :
59419
citations: 7
Reference
Tan H, Lu G, Dong H, Cho Y, Natalia A, Wang L, et al. A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery. Nat Commun. 2022;13:3720 pubmed publisher
Anderson R, Miller L, Isom S, Chou J, Pladna K, Schramm N, et al. Phase II trial of cytarabine and mitoxantrone with devimistat in acute myeloid leukemia. Nat Commun. 2022;13:1673 pubmed publisher
Liu K, Kong L, Graham D, Carey K, Xavier R. SAC1 regulates autophagosomal phosphatidylinositol-4-phosphate for xenophagy-directed bacterial clearance. Cell Rep. 2021;36:109434 pubmed publisher
Chen K, Yan R, Xiang L, Xu K. Excitation spectral microscopy for highly multiplexed fluorescence imaging and quantitative biosensing. Light Sci Appl. 2021;10:97 pubmed publisher
Sarraf S, Sideris D, Giagtzoglou N, Ni L, Kankel M, Sen A, et al. PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. Cell Rep. 2019;29:225-235.e5 pubmed publisher
Fogel A, Martin S, Hasson S. Application of Imaging-Based Assays in Microplate Formats for High-Content Screening. Methods Mol Biol. 2016;1439:273-304 pubmed publisher
Yamano K, Fogel A, Wang C, van der Bliek A, Youle R. Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy. elife. 2014;3:e01612 pubmed publisher
product information
Catalog Number :
59419
Product Name :
pBMN-mCherry-Parkin
article :
doi
id8877
pubmed_id24569479
bacterial resistance :
Ampicillin
cloning :
backbonepBMN-Z-LacZ
backbone_mutationlacZ is removed during cloning
backbone_origin
backbone_size4938
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth strain :
to make mCherry-Parkin stable cell line with retrovirus
origin :
37
pi :
alt_names
Park2
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5CCCTCAAAGTAGACGGCATC
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAR-JP, LPRS2, PARK2, PDJ
genePRKN
id5071
genbank_ids
NM_004562
mutation
namemCherry-Parkin
shRNA_sequence
size2142
species
9606
Homo sapiens
tags
locationN terminal on insert
tagmCherry
resistance markers :
604
tags :
Low Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA