This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCMV-myc-hIFITM3
catalog :
58461
citations: 4
Reference
Shilagardi K, Spear E, Abraham R, Griffin D, Michaelis S. The Integral Membrane Protein ZMPSTE24 Protects Cells from SARS-CoV-2 Spike-Mediated Pseudovirus Infection and Syncytia Formation. MBio. 2022;13:e0254322 pubmed publisher
Chmielewska A, Gómez Herranz M, Gach P, Nekulova M, Bagnucka M, Lipinska A, et al. The Role of IFITM Proteins in Tick-Borne Encephalitis Virus Infection. J Virol. 2022;96:e0113021 pubmed publisher
Kühnl A, Musiol A, Heitzig N, Johnson D, Ehrhardt C, Grewal T, et al. Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus. MBio. 2018;9: pubmed publisher
Chesarino N, McMichael T, Hach J, Yount J. Phosphorylation of the antiviral protein interferon-inducible transmembrane protein 3 (IFITM3) dually regulates its endocytosis and ubiquitination. J Biol Chem. 2014;289:11986-92 pubmed publisher
product information
Catalog Number :
58461
Product Name :
pCMV-myc-hIFITM3
article :
doi10.1074/jbc.M114.557694
id8683
pubmed_id24627473
bacterial resistance :
Ampicillin
cloning :
backbonepCMV-myc
backbone_mutation
backbone_originclontech
backbone_size3800
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expresses human IFITM3 with an N-terminal myc tag in mammalian cells.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5EcoRI
promoterCMV IE
sequencing_primer_3
sequencing_primer_5GATCCGGTACTAGAGGAACTGAAAAAC
site_3_destroyed
site_5_destroyed
entrez_gene
aliases1-8U, DSPA2b, IP15
geneIFITM3
id10410
genbank_ids
mutation
nameIFITM3
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagmyc
resistance markers :
2058
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA