This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
MDM2p-Mdm2-YFP
catalog :
53962
citations: 4
Reference
Strachotov xe1 D, Holoubek A, Wolfov xe1 K, Brodsk xe1 B, He x159 man P. Cytoplasmic localization of Mdm2 in cells expressing mutated NPM is mediated by p53. FEBS J. 2023;: pubmed publisher
Barrio E, Vecino R, Sánchez Morán I, Rodriguez C, Suárez Pindado A, Bolanos J, et al. Preconditioning-Activated AKT Controls Neuronal Tolerance to Ischemia through the MDM2-p53 Pathway. Int J Mol Sci. 2021;22: pubmed publisher
Jones R, Qian Y, Siciliano V, DiAndreth B, Huh J, Weiss R, et al. An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells. Nat Commun. 2020;11:5690 pubmed publisher
Lahav G, Rosenfeld N, Sigal A, Geva Zatorsky N, Levine A, Elowitz M, et al. Dynamics of the p53-Mdm2 feedback loop in individual cells. Nat Genet. 2004;36:147-50 pubmed
product information
Catalog Number :
53962
Product Name :
MDM2p-Mdm2-YFP
article :
doi10.1038/ng1293
id8423
pubmed_id14730303
bacterial resistance :
Kanamycin
cloning :
backbonepBSK+
backbone_mutationneomycin resistance gene added
backbone_origin
backbone_size7661
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expresses YFP tagged Mdm2 from MDM2 promoter
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5ECO47III
promoterMDM2
sequencing_primer_3
sequencing_primer_5unknown
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesACTFS, HDMX, LSKB, hdm2
geneMDM2
id4193
genbank_ids
mutation
nameMDM2
shRNA_sequence
size1485
species
9606
Homo sapiens
tags
locationC terminal on insert
tagEYFP
resistance markers :
1978
1977
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA