This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pMyc-CMV1-huTLR4mut-A896G
catalog :
53525
citations: 2
Reference
Sun P, Li D, Su M, Ren Q, Guo W, Wang J, et al. Cell membrane-bound toll-like receptor-1/2/4/6 monomers and -2 heterodimer inhibit enterovirus 71 replication by activating the antiviral innate response. Front Immunol. 2023;14:1187035 pubmed publisher
Kuo W, Lee T, Yang H, Chen C, Au Y, Lu Y, et al. LPS receptor subunits have antagonistic roles in epithelial apoptosis and colonic carcinogenesis. Cell Death Differ. 2015;22:1590-604 pubmed publisher
product information
Catalog Number :
53525
Product Name :
pMyc-CMV1-huTLR4mut-A896G
article :
doi10.1038/cdd.2014.240
id10263
pubmed_id25633197
bacterial resistance :
Ampicillin
cloning :
backbonepMyc-CMV1
backbone_mutationpFLAG-CMV is from Sigma. Flag to Myc modified by Dr. Golenbock.
backbone_originDr. Golenbock, University of Massachusetts Medical School
backbone_size4743
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
expression of mutant TLR4 in mammalian cells
origin :
37
pi :
alt_names
CD284
TOLL
TLR-4
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5NotI
promoterCMV
sequencing_primer_3C-CMV-24 TATTAGGACAAGGCTGGTGGGCAC
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesARMD10, CD284, TLR-4, TOLL
geneTLR4
id7099
genbank_ids
mutationA896G
nameTLR4 A896G
shRNA_sequence
size2400
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagMyc
resistance markers :
1954
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA