This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pEF-Bos-FLAG RIG-I MIII
catalog :
52877
citations: 4
Reference
Vaughn L, Frederick K, Burnett S, Sharma N, Bragg D, Camargos S, et al. DYT-PRKRA Mutation P222L Enhances PACT's Stimulatory Activity on Type I Interferon Induction. Biomolecules. 2022;12: pubmed publisher
Rocha R, Del Sarto J, Gomes G, Gonçalves M, Rachid M, Smetana J, et al. Type I interferons are essential while type II interferon is dispensable for protection against St. Louis encephalitis virus infection in the mouse brain. Virulence. 2021;12:244-259 pubmed publisher
Chang C, Liu H, Chang M, Chang S. Middle East Respiratory Syndrome Coronavirus Nucleocapsid Protein Suppresses Type I and Type III Interferon Induction by Targeting RIG-I Signaling. J Virol. 2020;94: pubmed publisher
Bamming D, Horvath C. Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2. J Biol Chem. 2009;284:9700-12 pubmed publisher
product information
Catalog Number :
52877
Product Name :
pEF-Bos-FLAG RIG-I MIII
article :
doi10.1074/jbc.M807365200
id8194
pubmed_id19211564
bacterial resistance :
Ampicillin
cloning :
backbonepEF-Bos-Flag
backbone_mutation
backbone_origin
backbone_size5500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expresses RIG-I with a mutation to motif III in mammalian cells
origin :
37
pi :
alt_names
RIG-I
retinoic acid-inducible gene 1
cloning
clone_methodUnknown
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3pEF-Bos-R
sequencing_primer_5pEF-Bos-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesDDX58, RIG-I, RIG1, RLR-1, SGMRT2
geneRIGI
id23586
genbank_ids
NM_014314
mutationT409A, S411A
nameDDX58
shRNA_sequence
size4700
species
9606
Homo sapiens
tags
locationN terminal on insert
tagFLAG
resistance markers :
1670
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA