pZac2.1 gfaABC1D-EGFP-Kir4.1 | Addgene 52874 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pZac2.1 gfaABC1D-EGFP-Kir4.1

catalog :

52874

citations: 4

Reference
Soto J, Jami Alahmadi Y, Chacon J, Moye S, Diaz Castro B, Wohlschlegel J, et al. Astrocyte-neuron subproteomes and obsessive-compulsive disorder mechanisms. Nature. 2023;616:764-773 pubmed publisher
Kelley K, Ben Haim L, Schirmer L, Tyzack G, Tolman M, Miller J, et al. Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength. Neuron. 2018;98:306-319.e7 pubmed publisher
Vagner T, Dvorzhak A, WÃ³jtowicz A, Harms C, Grantyn R. Systemic application of AAV vectors targeting GFAP-expressing astrocytes in Z-Q175-KI Huntington's disease mice. Mol Cell Neurosci. 2016;77:76-86 pubmed publisher
Tong X, Ao Y, Faas G, Nwaobi S, Xu J, Haustein M, et al. Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice. Nat Neurosci. 2014;17:694-703 pubmed publisher

product information

Catalog Number :

52874

Product Name :

pZac2.1 gfaABC1D-EGFP-Kir4.1

article :

doi	10.1038/nn.3691
id	9928
pubmed_id	24686787

bacterial resistance :

Ampicillin

cloning :

backbone

pZac 2.1

backbone_mutation

backbone_origin

backbone_size

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

AAV

Other

Adeno-Associated Virus ()

growth strain :

Express EGFP-Kir4.1 fusion protein in astrocytes

origin :

pi :

alt_names

Kcnj10

cloning

clone_method	Unknown
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3	EBV-rev
sequencing_primer_5	T7
site_3_destroyed
site_5_destroyed

entrez_gene

aliases
gene	Kcnj10
id	29718

genbank_ids

NM_031602

mutation

name

Kir4.1

shRNA_sequence

size

species

10116

Rattus norvegicus