This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pDEST 3x Flag-pcDNA5-FRT/T0-BRCA1
catalog :
52504
citations: 4
Reference
Taouis K, Vacher S, Guirouilh Barbat J, Camonis J, Formstecher E, Popova T, et al. WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer. Cancer Gene Ther. 2023;30:1144-1155 pubmed publisher
Luedeman M, Stroik S, Feng W, Luthman A, Gupta G, Ramsden D. Poly(ADP) ribose polymerase promotes DNA polymerase theta-mediated end joining by activation of end resection. Nat Commun. 2022;13:4547 pubmed publisher
Onyango D, Howard S, Neherin K, Yanez D, Stark J. Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination. Nucleic Acids Res. 2016;44:5702-16 pubmed publisher
Escribano D az C, Orthwein A, Fradet Turcotte A, Xing M, Young J, Tk J, et al. A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice. Mol Cell. 2013;49:872-83 pubmed publisher
product information
Catalog Number :
52504
Product Name :
pDEST 3x Flag-pcDNA5-FRT/T0-BRCA1
article :
doi10.1016/j.molcel.2013.01.001
id8122
pubmed_id23333306
bacterial resistance :
Ampicillin
cloning :
backbonepDEST 3' Triple Flag pcDNA5 FRT TO
backbone_mutation
backbone_origin
backbone_size6856
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
mammalian expression vector of BRCA1 wildtype siRNA resistant
origin :
37
pi :
alt_names
cloning
clone_methodUnknown
cloning_site_3
cloning_site_5
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP, RNF53
geneBRCA1
id672
genbank_ids
mutationsiRNA resistant sequence: AGTATAATC
nameBRCA1
shRNA_sequence
size1864
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagFlag
resistance markers :
2121
tags :
Unknown
terms :
Hygromycin
Blasticidin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA