This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLenti-EmGFP-LATS2/1 KD
catalog :
52085
citations: 4
Reference
Ouyang H, Luong P, Frodin M, Hansen S. p190A RhoGAP induces CDH1 expression and cooperates with E-cadherin to activate LATS kinases and suppress tumor cell growth. Oncogene. 2020;: pubmed publisher
Gargini R, Escoll M, Garcia E, García Escudero R, Wandosell F, Anton I. WIP Drives Tumor Progression through YAP/TAZ-Dependent Autonomous Cell Growth. Cell Rep. 2016;17:1962-1977 pubmed publisher
Lorthongpanich C, Jiamvoraphong N, Supraditaporn K, Klaihmon P, U Pratya Y, Issaragrisil S. The Hippo pathway regulates human megakaryocytic differentiation. Thromb Haemost. 2017;117:116-126 pubmed publisher
Yang Z, Nakagawa K, Sarkar A, Maruyama J, Iwasa H, Bao Y, et al. Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model. Mol Cell Biol. 2014;34:1607-21 pubmed publisher
product information
Catalog Number :
52085
Product Name :
pLenti-EmGFP-LATS2/1 KD
article :
doi10.1128/MCB.01346-13
id7997
pubmed_id24550007
bacterial resistance :
Ampicillin
cloning :
backbonepLenti4-EF/V5-DEST
backbone_mutationEmGFP and LATS2/1 KD were inserted into pLenti-EF/V5-DEST from pcDNA 6.2-GW/miR vector.
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
RNAi
growth notes :
Co-cistronic expression of LATS2/1 pre-miRNA with EmGFP as reporter.
growth strain :
Lentiviral RNAi vector for knockdown of LATS2 and LATS1. Co-expresses EmGFP as reporter
origin :
37
pi :
alt_names
cloning
clone_methodGateway Cloning
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3pBABE-3
sequencing_primer_5EF1a-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesWARTS, wts
geneLATS1
id9113
aliasesKPM
geneLATS2
id26524
genbank_ids
mutation
nameLATS2 and LATS1 miRNAs
shRNA_sequence
size
species
9606
Homo sapiens
tags
resistance markers :
1244
tags :
Unknown
terms :
Other
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA