This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pBABEpuro-CRAF
catalog :
51124
citations: 6
Reference
Mysore V, Zhou Z, Ambrogio C, Li L, Kapp J, Lu C, et al. A structural model of a Ras-Raf signalosome. Nat Struct Mol Biol. 2021;28:847-857 pubmed publisher
Zhou Z, Ambrogio C, Bera A, Li Q, Li X, Li L, et al. KRASQ61H preferentially signals through MAPK in a RAF dimer-dependent manner in non-small cell lung cancer. Cancer Res. 2020;: pubmed publisher
Nunns H, Goentoro L. Signaling pathways as linear transmitters. elife. 2018;7: pubmed publisher
Cope N, Candelora C, Wong K, Kumar S, Nan H, Grasso M, et al. Mechanism of BRAF Activation through Biochemical Characterization of the Recombinant Full-Length Protein. Chembiochem. 2018;19:1988-1997 pubmed publisher
Li S, Liu J, Tan J, Li L, Kaltreider M, Zhao J, et al. Inhibition of Raf1 ameliorates bleomycin-induced pulmonary fibrosis through attenuation of TGF-β1 signaling. Am J Physiol Lung Cell Mol Physiol. 2018;315:L241-L247 pubmed publisher
Rose J, Huang P, Camp N, Ye J, Leidal A, Goreshnik I, et al. A computationally engineered RAS rheostat reveals RAS-ERK signaling dynamics. Nat Chem Biol. 2017;13:119-126 pubmed publisher
product information
Catalog Number :
51124
Product Name :
pBABEpuro-CRAF
article :
doi
id7793
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepBABEpuro
backbone_mutation
backbone_origin
backbone_size5200
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth strain :
mammalian expression of wt CRAF
origin :
37
pi :
alt_names
RAF1
c-Raf
Raf-1
cloning
clone_methodGateway Cloning
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3pBABE 3'
sequencing_primer_5pBABE 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCMD1NN, CRAF, NS5, Raf-1, c-Raf
geneRAF1
id5894
genbank_ids
NM_002880.3
mutation
nameCRAF
shRNA_sequence
size1950
species
9606
Homo sapiens
tags
resistance markers :
338
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA