This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCDNA3 Flag MKK3b(Glu)
catalog :
50449
citations: 3
Reference
Wang S, Mi R, Cai Z, Wang Z, Zeng C, Xie Z, et al. DAPK1 Interacts with the p38 Isoform MAPK14, Preventing Its Nuclear Translocation and Stimulation of Bone Marrow Adipogenesis. Stem Cells. 2022;40:508-522 pubmed publisher
Cook P, Tabor G. Deciphering fact from artifact when using reporter assays to investigate the roles of host factors on L1 retrotransposition. Mob DNA. 2016;7:23 pubmed
Enslen H, Brancho D, Davis R. Molecular determinants that mediate selective activation of p38 MAP kinase isoforms. EMBO J. 2000;19:1301-11 pubmed
product information
Catalog Number :
50449
Product Name :
pCDNA3 Flag MKK3b(Glu)
article :
doi10.1093/emboj/19.6.1301
id2503
pubmed_id10716930
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
activates p38 in the signaling pathway
origin :
37
pi :
alt_names
MAP2K3 mitogen-activated protein kinase kinase 3
MKK3 isoform B
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5Hind III
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2
geneMAP2K3
id5606
genbank_ids
NM_145109.2
mutationchanged Serine 218 to Glutamic Acid, changed Threonine 222 to Glutamic Acid
nameMKK3b
shRNA_sequence
size1041
species
9606
Homo sapiens
tags
locationN terminal on insert
tagFlag
resistance markers :
106
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA