pCMV5-hBMPR-1A CA | Addgene 49527 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pCMV5-hBMPR-1A CA

catalog :

49527

citations: 2

Reference
Chen C, Kao Y, Yang P, Sung P, Wen Z, Chen J, et al. A Small Dibromotyrosine Derivative Purified From Pseudoceratina Sp. Suppresses TGF-Î² Responsiveness by Inhibiting TGF-Î² Type I Receptor Serine/Threonine Kinase Activity. J Cell Biochem. 2016;117:2800-2814 pubmed publisher
Varley J, McPherson C, Zou H, Niswander L, Maxwell G. Expression of a constitutively active type I BMP receptor using a retroviral vector promotes the development of adrenergic cells in neural crest cultures. Dev Biol. 1998;196:107-18 pubmed

product information

Catalog Number :

49527

Product Name :

pCMV5-hBMPR-1A CA

article :

doi	10.1006/dbio.1998.8853
id	7525
pubmed_id	9527884

bacterial resistance :

Ampicillin

cloning :

backbone

pCMV5

backbone_mutation

backbone_origin

Dr. David Russell, UTSW

backbone_size

4657

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

growth notes :

The BMPR-1A insert in this plasmid contains P2A and K208R mutations when compared to GenBank reference sequence NP_004320.2. These mutations are not a concern for the function of the plasmid, as described in the associated publication.

growth strain :

expresses constitutively active human BMP receptor 1A

origin :

pi :

alt_names

BMPR-1A

Alk3

cloning

clone_method	Restriction Enzyme
cloning_site_3	XbaI
cloning_site_5	HindIII
promoter	CMV
sequencing_primer_3	hGH-PA-R
sequencing_primer_5	CMV-F
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	10q23del, ACVRLK3, ALK-3, ALK3, BMPR-1A, CD292, SKR5
gene	BMPR1A
id	657

genbank_ids

mutation

constitutively active mutation (Q233D); also P2A and K208R

name

BMPR-1A CA

shRNA_sequence

size

species

9606

Homo sapiens