This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA-HA-ER Y537S
catalog :
49499
citations: 2
Reference
Li Z, McGinn O, Wu Y, Bahreini A, Priedigkeit N, Ding K, et al. ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation. Nat Commun. 2022;13:2011 pubmed publisher
Barua D, Abbasi B, Gupta A, Gupta S. XBP1 increases transactivation of somatic mutants of ESR1 and loss of XBP1 reverses endocrine resistance conferred by gain-of-function Y537S ESR1 mutation. Heliyon. 2020;6:e05217 pubmed publisher
product information
Catalog Number :
49499
Product Name :
pcDNA-HA-ER Y537S
article :
doi
id7519
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1 (+)
backbone_mutation
backbone_originInvitrogen
backbone_size5428
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expresses HA-tagged ER Y537S mutant in mammalian cells
origin :
37
pi :
alt_names
ER
estrogen receptor
cloning
clone_methodRestriction Enzyme
cloning_site_3ApaI
cloning_site_5BamHI
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesER, ESR, ESRA, ESTRR, Era, NR3A1
geneESR1
id2099
genbank_ids
mutationTyrosine 537 to Serine
nameESR1
shRNA_sequence
size1800
species
9606
Homo sapiens
tags
locationN terminal on insert
tagHA
plasmid copy :
Addgene Plasmid 28230: pEGFP-C1-ER alpha (Depositor: Michael Mancini)
resistance markers :
1767
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA