This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA-HA-ER WT
catalog :
49498
citations: 8
Reference
Costa A, Lemes R, Bartolomeo C, Nunes T, Pereira G, Oliveira R, et al. Overexpression of estrogen receptor GPER1 and G1 treatment reduces SARS-CoV-2 infection in BEAS-2B bronchial cells. Mol Cell Endocrinol. 2022;558:111775 pubmed publisher
Li X, Zhuo S, Zhuang T, Cho Y, Wu G, Liu Y, et al. YAP inhibits ERα and ER+ breast cancer growth by disrupting a TEAD-ERα signaling axis. Nat Commun. 2022;13:3075 pubmed publisher
Li Z, McGinn O, Wu Y, Bahreini A, Priedigkeit N, Ding K, et al. ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation. Nat Commun. 2022;13:2011 pubmed publisher
Barua D, Abbasi B, Gupta A, Gupta S. XBP1 increases transactivation of somatic mutants of ESR1 and loss of XBP1 reverses endocrine resistance conferred by gain-of-function Y537S ESR1 mutation. Heliyon. 2020;6:e05217 pubmed publisher
Chapple R, Hu T, Tseng Y, Liu L, Kitano A, Luu V, et al. ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response. elife. 2018;7: pubmed publisher
Yang H, Yu N, Xu J, Ding X, Deng W, Wu G, et al. SMURF1 facilitates estrogen receptor ɑ signaling in breast cancer cells. J Exp Clin Cancer Res. 2018;37:24 pubmed publisher
Shi J, Chen S, Guo C, Li Y, Ding J, Meng L. The mTOR inhibitor AZD8055 overcomes tamoxifen resistance in breast cancer cells by down-regulating HSPB8. Acta Pharmacol Sin. 2018;39:1338-1346 pubmed publisher
Lahsaee S, Corkery D, Anthes L, Holly A, Dellaire G. Estrogen receptor alpha (ESR1)-signaling regulates the expression of the taxane-response biomarker PRP4K. Exp Cell Res. 2016;340:125-31 pubmed publisher
product information
Catalog Number :
49498
Product Name :
pcDNA-HA-ER WT
article :
doi
id7519
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1 (+)
backbone_mutation
backbone_originInvitrogen
backbone_size5428
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expresses HA-tagged ER wild-type in mammalian cells
origin :
37
pi :
alt_names
ER
estrogen receptor
cloning
clone_methodRestriction Enzyme
cloning_site_3ApaI
cloning_site_5BamHI
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesER, ESR, ESRA, ESTRR, Era, NR3A1
geneESR1
id2099
genbank_ids
mutation
nameESR1
shRNA_sequence
size1800
species
9606
Homo sapiens
tags
locationN terminal on insert
tagHA
plasmid copy :
Addgene Plasmid 28230: pEGFP-C1-ER alpha (Depositor: Michael Mancini)
resistance markers :
1767
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA