This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
CaV1.3e[8a,11,31b, 32,42a]
catalog :
49333
citations: 8
Reference
Chin M, Kaeser P. The intracellular C-terminus confers compartment-specific targeting of voltage-gated Ca2+ channels. bioRxiv. 2023;: pubmed publisher
Jeong S, Rhee J, Lee J. Snapin Specifically Up-Regulates Cav1.3 Ca2+ Channel Variant with a Long Carboxyl Terminus. Int J Mol Sci. 2021;22: pubmed publisher
McArthur J, Munasinghe N, Finol Urdaneta R, Adams D, Christie M. Spider Venom Peptide Pn3a Inhibition of Primary Afferent High Voltage-Activated Calcium Channels. Front Pharmacol. 2020;11:633679 pubmed publisher
Dickerson M, Dadi P, Butterworth R, Nakhe A, Graff S, Zaborska K, et al. Tetraspanin-7 regulation of L-type voltage-dependent calcium channels controls pancreatic β-cell insulin secretion. J Physiol. 2020;598:4887-4905 pubmed publisher
Sahu G, Asmara H, Zhang F, Zamponi G, Turner R. Activity-Dependent Facilitation of CaV1.3 Calcium Channels Promotes KCa3.1 Activation in Hippocampal Neurons. J Neurosci. 2017;37:11255-11270 pubmed publisher
Vivas O, Moreno C, Santana L, Hille B. Proximal clustering between BK and CaV1.3 channels promotes functional coupling and BK channel activation at low voltage. elife. 2017;6: pubmed publisher
Moreno C, Dixon R, Tajada S, Yuan C, Opitz Araya X, Binder M, et al. Ca(2+) entry into neurons is facilitated by cooperative gating of clustered CaV1.3 channels. elife. 2016;5: pubmed publisher
Xu W, Lipscombe D. Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines. J Neurosci. 2001;21:5944-51 pubmed
product information
Catalog Number :
49333
Product Name :
CaV1.3e[8a,11,31b, 32,42a]
article :
doi
id3699
pubmed_id11487617
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA6/V5-His ABC
backbone_mutation
backbone_originInvitrogen
backbone_size5100
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Isolated from superior cervical ganglia. For more information about this plasmid: http://neuroscience.brown.edu/LipscombeLab/homepage/otherpages/clonespage/clonespage1.htm
growth strain :
Repaired Addgene #26576 to agree with the rat ref sequence. Repairs are @: nt 3310 (GTG->GCG) [Val->Ala]; nt 731 (TCA->GGA) [Ser->Gly].
inserts :
Top10F'
origin :
30
pi :
alt_names
calcium channel, voltage-dependent, L type, alpha 1D subunit
Cav1.3
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5NheI
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-Fwd
site_3_destroyed
site_5_destroyed
entrez_gene
aliases
geneCacna1d
id29716
genbank_ids
mutationContains exons 8a, 11, 31b and 42a.Deletion of exon 32.
nameCACNA1D
shRNA_sequence
size5700
species
10116
Rattus norvegicus
tags
resistance markers :
813
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA