This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pIRES2-EGFP-p53 WT
catalog :
49242
citations: 6
Reference
Kelishadi M, Shahsavarani H, Tabarraei A, Shokrgozar M, Teimoori Toolabi L, Azadmanesh K. The chicken chorioallantoic membrane model for isolation of CRISPR/cas9-based HSV-1 mutant expressing tumor suppressor p53. PLoS ONE. 2023;18:e0286231 pubmed publisher
Walter M, Mayr F, Hanna B, Cookson V, Mortusewicz O, Helleday T, et al. NUDT22 promotes cancer growth through pyrimidine salvage. Oncogene. 2023;42:1282-1293 pubmed publisher
Guiley K, Shokat K. A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability. Cancer Discov. 2023;13:56-69 pubmed publisher
Ticha I, Hojny J, Michálková R, Kodet O, Krkavcová E, Hajkova N, et al. A comprehensive evaluation of pathogenic mutations in primary cutaneous melanomas, including the identification of novel loss-of-function variants. Sci Rep. 2019;9:17050 pubmed publisher
Yuan F, Wang J, Li R, Zhao X, Zhang Y, Liu B, et al. A New Regulatory Mechanism Between P53 And YAP Crosstalk By SIRT1 Mediated Deacetylation To Regulate Cell Cycle And Apoptosis In A549 Cell Lines. Cancer Manag Res. 2019;11:8619-8633 pubmed publisher
Lin S, Karoly E, Taatjes D. The human ?Np53 isoform triggers metabolic and gene expression changes that activate mTOR and alter mitochondrial function. Aging Cell. 2013;12:863-72 pubmed publisher
product information
Catalog Number :
49242
Product Name :
pIRES2-EGFP-p53 WT
article :
doi10.1111/acel.12108
id7450
pubmed_id23734707
bacterial resistance :
Kanamycin
cloning :
backbonepIRES2-EGFP
backbone_mutation
backbone_originclonetch
backbone_size5300
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
expresses human wt p53 and EGFP in mammalian cells
origin :
37
pi :
alt_names
tumor protein p53
cloning
clone_methodRestriction Enzyme
cloning_site_3KpnI
cloning_site_5NheI
promoterCMV
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCC7, BMFS5, LFS1, P53, TRP53
geneTP53
id7157
genbank_ids
mutation
namep53
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagIRES-EGFP
resistance markers :
1749
tags :
Low Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA