pCDEF3 hTIM3 (no tag) | Addgene 49212 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pCDEF3 hTIM3 (no tag)

catalog :

49212

citations: 4

Reference
Chongsaritsinsuk J, Steigmeyer A, Mahoney K, Rosenfeld M, Lucas T, Smith C, et al. Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE. Nat Commun. 2023;14:6169 pubmed publisher
Smith C, Li A, Krishnamurthy N, Lemmon M. Phosphatidylserine binding directly regulates TIM-3 function. Biochem J. 2021;478:3331-3349 pubmed publisher
Lake C, Voss K, Bauman B, Pohida K, Jiang T, Dveksler G, et al. TIM-3 drives temporal differences in restimulation-induced cell death sensitivity in effector CD8+ T cells in conjunction with CEACAM1. Cell Death Dis. 2021;12:400 pubmed publisher
Lee J, Su E, Zhu C, Hainline S, Phuah J, Moroco J, et al. Phosphotyrosine-dependent coupling of Tim-3 to T-cell receptor signaling pathways. Mol Cell Biol. 2011;31:3963-74 pubmed publisher

product information

Catalog Number :

49212

Product Name :

pCDEF3 hTIM3 (no tag)

article :

doi	10.1128/MCB.05297-11
id	7439
pubmed_id	21807895

bacterial resistance :

Ampicillin

cloning :

backbone

pCDEF3

backbone_mutation

backbone_origin

backbone_size

6094

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

growth strain :

expresses human Tim3

origin :

pi :

alt_names

hepatitis A virus cellular receptor 2

Tim-3

Havcr2

cloning

clone_method	Restriction Enzyme
cloning_site_3	NotI
cloning_site_5	KpnI
promoter	EF1a
sequencing_primer_3	SP6
sequencing_primer_5	EF1a-F
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	CD366, HAVcr-2, KIM-3, SPTCL, TIM3, TIMD-3, TIMD3, Tim-3
gene	HAVCR2
id	84868

genbank_ids

mutation

name

Tim3

shRNA_sequence

size

species

9606

Homo sapiens