This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
mCh-Rab5
catalog :
49201
citations: 21
Reference
Li X, Jiang Q, Song G, Barkestani M, Wang Q, Wang S, et al. A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells. Nat Commun. 2023;14:3002 pubmed publisher
Rossatti P, Redpath G, Ziegler L, Samson G, Clamagirand C, Legler D, et al. Rapid increase in transferrin receptor recycling promotes adhesion during T cell activation. BMC Biol. 2022;20:189 pubmed publisher
Duncan E, Han K, Trout M, Prekeris R. Ubiquitylation by Rab40b/Cul5 regulates Rap2 localization and activity during cell migration. J Cell Biol. 2022;221: pubmed publisher
Banerjee P, Xiao G, Tan X, Zheng V, Shi L, Rabassedas M, et al. The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells. Nat Commun. 2021;12:6354 pubmed publisher
Sønder S, Häger S, Heitmann A, Frankel L, Dias C, Simonsen A, et al. Restructuring of the plasma membrane upon damage by LC3-associated macropinocytosis. Sci Adv. 2021;7: pubmed publisher
Joshi A, Ragusa J, Prinz W, Cohen S. Multiple C2 domain-containing transmembrane proteins promote lipid droplet biogenesis and growth at specialized endoplasmic reticulum subdomains. Mol Biol Cell. 2021;32:1147-1157 pubmed publisher
Ecker M, Redpath G, Nicovich P, Rossy J. Quantitative visualisation of endocytic trafficking through photoactivation of fluorescent proteins. Mol Biol Cell. 2021;:mbcE20100669 pubmed publisher
Mahendran T, Suresh S, Garimella L, Manjithaya R. Soluble 4R0N Tau Abrogates Endocytic Vesicular Dynamics. Front Aging Neurosci. 2020;12:537712 pubmed publisher
Scremin E, Agostini M, Leparulo A, Pozzan T, Greotti E, Fasolato C. ORAI2 Down-Regulation Potentiates SOCE and Decreases Aβ42 Accumulation in Human Neuroglioma Cells. Int J Mol Sci. 2020;21: pubmed publisher
Jiang X, Jia X, Sun J, Qi C, Lu L, Wang Y, et al. Overexpressed coiled-coil domain containing protein 8 (CCDC8) mediates newly synthesized HIV-1 Gag lysosomal degradation. Sci Rep. 2020;10:11416 pubmed publisher
Gonzales B, de Rocquigny H, Beziau A, Durand S, Burlaud Gaillard J, Lefebvre A, et al. Type I Phosphatidylinositol-4-Phosphate 5-Kinases α and γ Play a Key Role in Targeting HIV-1 Pr55Gag to the Plasma Membrane. J Virol. 2020;94: pubmed publisher
Xie C, Jiang B, Qin L, Tellides G, Kirkiles Smith N, Jane Wit D, et al. Complement-activated interferon-γ-primed human endothelium transpresents interleukin-15 to CD8+ T cells. J Clin Invest. 2020;130:3437-3452 pubmed publisher
Schwerk J, Soveg F, Ryan A, Thomas K, Hatfield L, Ozarkar S, et al. RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions. Nat Immunol. 2019;20:1610-1620 pubmed publisher
Redpath G, Ecker M, Kapoor Kaushik N, Vartoukian H, Carnell M, Kempe D, et al. Flotillins promote T cell receptor sorting through a fast Rab5-Rab11 endocytic recycling axis. Nat Commun. 2019;10:4392 pubmed publisher
Lin A, Gill K, Castañeda M, Matucci I, Eder N, Claxton S, et al. Chemical genetic identification of GAK substrates reveals its role in regulating Na+/K+-ATPase. Life Sci Alliance. 2018;1:e201800118 pubmed publisher
Tábara L, Vicente J, Biazik J, Eskelinen E, Vincent O, Escalante R. Vacuole membrane protein 1 marks endoplasmic reticulum subdomains enriched in phospholipid synthesizing enzymes and is required for phosphoinositide distribution. Traffic. 2018;19:624-638 pubmed publisher
Shi J, Xiong R, Zhou T, Su P, Zhang X, Qiu X, et al. HIV-1 Nef Antagonizes SERINC5 Restriction by Downregulation of SERINC5 via the Endosome/Lysosome System. J Virol. 2018;92: pubmed publisher
Gorvin C, Rogers A, Hastoy B, Tarasov A, Frost M, Sposini S, et al. AP2σ Mutations Impair Calcium-Sensing Receptor Trafficking and Signaling, and Show an Endosomal Pathway to Spatially Direct G-Protein Selectivity. Cell Rep. 2018;22:1054-1066 pubmed publisher
Samson E, Tsao D, Zimak J, McLaughlin R, Trenton N, Mace E, et al. The coordinating role of IQGAP1 in the regulation of local, endosome-specific actin networks. Biol Open. 2017;6:785-799 pubmed publisher
Tábara L, Escalante R. VMP1 Establishes ER-Microdomains that Regulate Membrane Contact Sites and Autophagy. PLoS ONE. 2016;11:e0166499 pubmed publisher
Friedman J, Webster B, Mastronarde D, Verhey K, Voeltz G. ER sliding dynamics and ER-mitochondrial contacts occur on acetylated microtubules. J Cell Biol. 2010;190:363-75 pubmed publisher
product information
Catalog Number :
49201
Product Name :
mCh-Rab5
article :
doi10.1083/jcb.200911024
id7421
pubmed_id20696706
bacterial resistance :
Kanamycin
cloning :
backbonemCh-alpha tubulin (Addgene plasmid 49149)
backbone_mutation
backbone_originVoeltz lab
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
expression of Rab5 fused to mCherry
origin :
37
pi :
alt_names
RAB5B, member RAS oncogene family
cloning
clone_methodUnknown
cloning_site_3
cloning_site_5
promoterCMV
sequencing_primer_3
sequencing_primer_5mCherry-F (ccccgtaatgcagaagaaga)
site_3_destroyed
site_5_destroyed
entrez_gene
aliases
geneRAB5B
id5869
genbank_ids
mutation
nameRab5
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagmCherry
resistance markers :
1740
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA